'Ldl' presentation slideshows

Lipid Absorption and Mobilization. Lipoproteins. Transport water insoluble TAG, cholesterol and cholesterol-esters throughout circulatory system Hydrophobic core containing TAG and cholesterol-esters Hydrophillic surface made of proteins (apoproteins) and phospholipids). Lipoproteins.

Atherosclerosis & Lipoprotein Metabolism. Arteriosclerosis= hardening of the arteries. ↑Serum cholesterol (above 4mmol/L)  ↑risk of coronary heart disease <4mmol/L level of plasma cholesterol is considered to be safe ↑LDL  ↑risk of coronary heart disease while,

Insert Title Here. Presented By: Name Title. Heart disease, stroke and other cardiovascular diseases are the No. 1 killer of Americans Over 2,600 Americans die of cardiovascular disease each day. 1 US heart disease prevalence is projected to double in the next century. 2

Novel therapies for the prevention of atherosclerotic vascular disease. Prof. John Kastelein Academic Medical Centre Amsterdam, The Netherlands. Novel Approaches to Modify Lipids and Lipoproteins. Low Density Lipoprotein High Density Lipoprotein Triglyceride Rich Lipoproteins

NMR Lipoprofile : More than LDL -P. Tara Dall, MD, FNLA Advanced Lipidology Delafield, Wisconsin Diplomate , American Board of Clinical Lipidology www.advlip.com. Weight of Evidence LDL-P more predictive than LDL-C. 213 NMR related papers published to Date.

Lipid Disorder Management - Evidence Based Approach…. Dr Gaurav Chaudhary MD,DM Cardiology Assistant Professsor Department of Cardiology. Global Health Estimates: Key figures and tables. June 2014 Department of Health Statistics and Information Systems. Burden of CVD Is Enormous.

%TG. %Chol. LPE. Şilomikron. 86. 3. Origin. VLDL. 55. 12. Pre- . IDL. 23. 29. Pre- /. LDL. 6. 42. . HDL. 3. 15. . Lp(a). (LDL). (LDL). Pre- . Lipoprotein sınıflandırılması. Tip. Buzdolabı. LPE. LPs. I. Pos, clear. Normal. TG (chylos). IIa. Neg, clear.

Massive Hypertriglyceridaemia : A complete white-out,. -100. B. VLDL. LPL. B. B. -48. E. CIII. CIII. R. LIVER. B. LDL-R. E. LPL. Chylomicrons. IDL. E. LRP. SR-B1. CII. CE+FC. CE. E. TG. CII. AI. HL. B. HDL. CETP. LDL. LCAT. CE. FC. AI. AI. FC.

第十一章 血脂及血浆脂蛋白检验. 血脂、血浆脂蛋白及载脂蛋白检验的重要性. 动脉粥样硬化 (atherosclerosis, AS). 冠心病急性事件 （不稳定型心绞痛、急性心肌梗死和冠脉猝死）. 临床常规血脂和脂蛋白测定项目 : 总胆固醇（totalcholesterol，TC，包括FC和CE） 甘油三酯 (TG) 高密度脂蛋白－胆固醇(HDL-C) 低密度脂蛋白－胆固醇(LDL- C) 载脂蛋白等。. 本章内容概要. 第一节 概述 第二节 血脂、脂蛋白及载脂蛋白测定. 教学目标和要求.

Approach to the Management of Hypertriglyceridemia. Timothy A. Denton, M.D. Attending Cardiologist High Desert Heart Institute Victorville, CA. Outline. Lipids / Triglyceride metabolism Etiology of hypertriglyceridemia Therapy of hypertriglyceridemia Special considerations.

2011 Mgr. Petra Hirsova. Lipid-lowering drugs. Plasma lipids. Cholesterol, triglycerides, phospholipids , free fatty acids Transported as lipoproteins Core – hydrofobic lipids : cholesteryl esters , triglycerides Coat – hydro philic lipids : cholesterol, phospholipids.

Pathogenesis of Atherosclerosis. Judith Berliner, Ph.D. Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at UCLA. Fatty Streak. Early Fibrous Plaque. Advanced Plaque. Thrombus. Ages of Progression Fatty Streak – 0-30 Fibrous Plaque – 30-50

Note Midterm - 4 March in class. Note Signal peptide-A sequence of amino acids that determine whether a protein will be formed on the rough endoplasmic reticulum or on free ribosomes . Note: all protein synthesis begins on free ribosomes. Conversion of 70 mg/dl glucose to 3.9 mmol/L.

ISCHEMIC HEART DISEASE. GROUP B. Medication history. Mr JB, aged 45 years, has been taking the following medications on a regular basis for at least 2 years. Atorvostatin 10mg mane Metoprolol 100mg BD Prednisolone 5mg 1.5 D. Recent blood test.

Lipoprotein Structures, Function and Metabolism (2). Lipoproteins in plasma. Density Mobility Component CM CM TG rich

Why study statins?. #1 & #2 selling drugs in the world are statins – these two drugs account for 5% of the entire United States spending on drugs ($11.2 billion dollars), since Heart disease is the #1 killer in industrialized countries The poor prognosis of homozygous FH patients.

Agents Used to Treat Hyperlipidemia. Transportation of Lipids. Lipoproteins serve to transport lipids from tissue to tissue and participate in lipid metabolism. They consist of proteins and lipids and can be grouped into various categories based on their density.

第 22 章 动脉粥样硬化的临床用药 p 274 秦大莲 Department of pharmacology. 调节血脂药 扩张血管药 抗血小板药. Brief description. 概述（了解） 概念 AS 的形成过程 治疗 AS 常用药物（掌握） 抗 AS 药的新趋向（了解）. A. 危险因素. AS. 一、动脉粥样硬化 ( Atherosclerosis,AS ) 概念. 冠心病、 心肌梗死. 间歇性跛行. 脑血栓、 脑梗死. ㈠ 危险因素. 传统危险因素 血脂代谢障碍 高血压 糖尿病 肥胖. 非传统的危险因素

Genetics of Cardiovascular Disease. John N. Hamaty D.O. FACC, FACOI. Cardiovascular Genetics. Environmental causes- trauma, malnutrition, drug abuse-defined by body response- phenotype Genotype- how patient suffers or recovers

Clinical Biochemistry Aspects of Cardiovascular Disease Dr Vivion Crowley MRCPath FRCPI Consultant Chemical Pathologist Biochemistry Department St James’s Hospital. Atherosclerosis is a major cause of morbidity and mortality. Clinically manifests as Coronary Heart Disease (CHD)