'Kinase' presentation slideshows

Medical Biochemistry

Medical Biochemistry. Glycolysis/TCA/ETS Robert F. Waters, PhD. Glycolysis(Introduction). Glucose + 2 ADP + 2 NAD + + 2 P i -----> 2 Pyruvate + 2 ATP + 2 NADH + 2 H + Cofactors needed Mg++ for ATP Ca++, Zn++, Cd++ for absorption of glucose. Glycolysis. Anaerobic (Hypoxia)

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Protein phosphorylation in modulation of cell functions

Protein phosphorylation in modulation of cell functions. Jau-Song Yu ( ??? ) Department of Cell and Molecular Biology, Institute of Basic Medical Sciences, Medical College of Chang Gung University. ( ??????????????? ). Reversible Phosphorylation of Proteins. OH. Protein/Enzyme.

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Growth Factors and Receptor Tyrosine Kinases

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Coordinated regulation of glycolysis/gluconeogenesis

Coordinated regulation of glycolysis/gluconeogenesis. Regulation of glycolysis. Hexokinase Phosphofructokinase-1 Pyruvate kinase. Hexokinase. There are four isozymes (I, II, III and IV) of hexokinase encoded by four different genes.

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En z yme- linked Cell Surface Receptors

En z yme- linked Cell Surface Receptors. 16 April 2007. Mechanism of PDGF signal transduction. En z yme- linked Cell Surface Receptors. Receptor Tyrosine kinases: phosphorylate specific tyrosines

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CLASSIFICATION AND CHARACTERIZATION OF NATURAL PROTEIN INHIBITORS OF PROTEIN KINASES

CLASSIFICATION AND CHARACTERIZATION OF NATURAL PROTEIN INHIBITORS OF PROTEIN KINASES AGATA MEGLICZ 1 , JACEK LELUK 1 , BOGDAN LESYNG 1,2 1 Interdisciplinary Centre for Mathematical and Computational Modelling (ICM), Warsaw University, Poland

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The Well-Connected Cell

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The Two-Signal Model of T-cell Activation

The Two-Signal Model of T-cell Activation. DC. T cell. CD4 or CD8. 1+2=Full activation. 1. TCR. MHC. 2. COSTIMULATION. Experimental evidences for the two signal model of T cell activation Experimental evidences that CD28 is a costimulatory receptor

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Coordinated regulation of glycolysis/gluconeogenesis

Coordinated regulation of glycolysis/gluconeogenesis. High blood glucose. Insulin secretion. Synthesis of hexokinase II, PFK-1, pyruvate kinase. Movement of GLUT4 to plasma membrane of myocyte. Activation of insulin-sensitive protein kinase. Activation of protein kinase B. p.903. p.887.

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Intercellular communication Intracellular signals Gene regulation

Signal transduction: receptor gene. 1. Intercellular communication Intracellular signals Gene regulation. 2. Ligand. 3. Surface receptor. cell. Intracellular receptor. nucleus. Gene. 1- TF activation via signalling cascades 2- TF activation at the receptor

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Regulation of Binding of Lamin B Receptor to Chromatin by SR

Regulation of Binding of Lamin B Receptor to Chromatin by SR Protein Kinase and cdc2 Kinase in Xenopus Egg Extracts. Takano et cl.,(2004) J. Bio. Chem. 279 13265-13271. ???? 91390410 ???. ????. Xenopus egg : ??? cell cycle ???? , ??? ATP ???? , ????????????? .

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Phospholipids, Phosphoinositols & Eicosanoids

Phospholipids, Phosphoinositols & Eicosanoids. Phospholipids, Phosphoinositols & Eicosanoids. Common types of Phospholipids:. Phospholipids, Phosphoinositols & Eicosanoids. Second messenger released through hydrolysis by phospholipases and/or

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Overview of Our Integrated Proteomics and Bioinformatics Services Platform

Overview of Our Integrated Proteomics and Bioinformatics Services Platform The Systems Proteomics Company 2011 March 25. The Kinexus Discovery Platform. KINEX MICROARRAY SERVICES. KINETWORKS BLOTTING SERVICES. MASS SPEC SERVICES. PROBE PRODUCTION SERVICES. IN VIVO SERVICES.

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MICR 304 Immunology & Serology

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Introduction

Introduction to AP-1. Introduction . Tumor necrosis factor- a (TNF a ) is a pro-inflammatory cytokine important in immune responses TNF a inhibits cAMP-stimulated Cyp17 transcription TNF a activates protein kinase C in Leydig cells

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Protein Kinases

Protein Kinases. Lampros Mavrogiannis (Newcastle 10/01/2008). The Protein Kinase Motif: Structure. Ancient eukaryotic motif. typically ~250 aa long. Two distinct domains. Cleft for substrate binding. Provides a conserved framework but also flexibility. The Protein Kinase Motif: Structure.

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Kristine Briedis Journal Club 17 April 2006

Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and structural diversity Milanesi et al. BMC Bioinformatics Dec 2005. Kristine Briedis Journal Club 17 April 2006. Overview. Analysis of the human kinome

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THE BIOLOGY OF CANCER

THE BIOLOGY OF CANCER. A group of diseases identified by uncontrolled cell growth and proliferation. Normal cell growth. Abnormal cell growth. Viruses. Genetic make-up. Immune status. Radiation. Carcinogens. DEVELOPMENT OF CANCER. First Mutation. Second Mutation.

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