ADAPTIVE IMMUNE RESPONSE. Immune response to infections 1. Innate response Neutrophils, macrophages, NK cells at site of infection 2. Initiation of adaptive response iDCs phagocytose Ag and take to nodes DCs present Ag to T cells Get specific helper (CD4) T cellsBy sawyer
PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Lee KY, et al. Science 308:114-118(2005) Chen-Chung Lin, Dep. of Cell Biology. Introduction (TCR-CD3 complex ). TCR-CD3 complex. (Immunoreceptor tyrosine-based activation motifs). Signaling cascade.By halen
Mario J. Grijalva, Ph.D. (pronounced gree-HALL-va). Irvine 333 3-2192 email@example.com http://www.oucom.ohiou.edu/dbms-grijalva/teaching.htm. Signaling through lymphocyte receptors . Overview Clustering Phosphorylation Signal trasduction Receptor signaling pathways Antigen receptorsBy abeni
Lupus nephritis. review. Introduction. Tissue injury can affect nearly everyorgan, however, it is the damage to the kidney that is largely responsible for morbidity and mortality Within the kidney the expression of SLE is heterogeneous.By paul
Ch 9:T cell receptor. Where we’re going. Structure of the TCR- alpha and beta chains ( αβ ) The γδ Tcells- know a bit about them The CD3 components and signal transduction-cover much, responsible for just a few concepts. Alloreactivity. Review of TCR’s.By cicely
Chapter 6 Signaling Through Immune System Receptors. Ig, TCR, cytokine receptors signal transduction is the change of a signal from one form to another (i.e., passing information along in different forms). Overview. Events controlled by signaling Development, Activation, Homing, DeathBy cedric
Lymphocyte Signaling. What is signaling? The present concepts in Transmembrane receptor mediated signaling pathways. Antigen receptor complexes and signaling. Signaling---Gene transcription Other signaling pathways & Death. Receptor Crosslinking. Receptor ClusteringBy inez
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