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Hsp70 - PowerPoint PPT Presentation


Molecular Chaperones

Molecular Chaperones

Molecular Chaperones. The Hsp70 Super-family. Pathways For Protein Folding. Protein Folding in Cells Occurs in a Crowded Environment where Misfolding & Aggregation are Favored. Hsp 70 Family Proteins Assist Protein Folding in an Energy Dependent Process.

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344 views • 16 slides



DNAk = HSP70

DNAk = HSP70

DNAk = HSP70. Anfinsen Cage. 1-2) SRP binds leader peptide (pausing translation), which will take it to the proper location 3) Once in place SRP falls off and the ribosome continues to translate protein 4) A peptidase cleaves the leader peptide and then BIP

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358 views • 11 slides


Figure 1 . Expression of CIRBM(A), RBM3(B) and HSP70(C) in the infarction with necrotic

Figure 1 . Expression of CIRBM(A), RBM3(B) and HSP70(C) in the infarction with necrotic

A. B. C. Figure 1 . Expression of CIRBM(A), RBM3(B) and HSP70(C) in the infarction with necrotic neural tissue. CIRBM and HSP70 were weakly expressed surrounding infarct area. RBM3 was intensively expressed in the cells and endothelial cells of blood vessels. A. B. C.

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223 views • 6 slides


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