'Homology modeling' presentation slideshows

DockoMatic : Automated Tool for Homology Modeling and Docking Studies

Tutorial. DockoMatic : Automated Tool for Homology Modeling and Docking Studies. Learning Objectives. I. Create & validate a protein homology model II. Use molecular docking to calculate the binding energy for a drug to the protein III. Assessment of docking results

1.08k views • 86 slides

Anastasia Nikolskaya PIR (Protein Information Resource), Georgetown University Medical Center

FUNCTIONAL ANALYSIS OF PROTEIN SEQUENCES: ANNOTATION AND FAMILY CLASSIFICATION. Anastasia Nikolskaya PIR (Protein Information Resource), Georgetown University Medical Center. Problem:. Most new protein sequences come from genome sequencing projects Many have unknown functions

725 views • 55 slides

Protein structure prediction.

Protein structure prediction. Protein folds. Fold definition: two folds are similar if they have a similar arrangement of SSEs (architecture) and connectivity (topology). Sometimes a few SSEs may be missing.

554 views • 48 slides

Lab 9.3a: Homology Modeling

Lab 9.3a: Homology Modeling. Boris Steipe boris.steipe@utoronto.ca http://biochemistry.utoronto.ca/steipe Departments of Biochemistry and Molecular and Medical Genetics Program in Proteomics and Bioinformatics University of Toronto. Concepts.

580 views • 43 slides

Molecular Modeling & Drug Design

Molecular Modeling & Drug Design. Xin Chen xinchen@zju.edu.cn. Molecular Modeling and Drug Design. Homology modeling Docking QSAR/QSPR. Homology modeling. Why Molecular modeling?.

2.46k views • 41 slides

Protein Sequence Analysis - Overview

Protein Sequence Analysis - Overview. Raja Mazumder Scientific Coordinator, PIR Research Assistant Professor, Department of Biochemistry and Molecular Biology Georgetown University Medical Center. NIH Proteomics Workshop 2006. Overview.

491 views • 35 slides

TTCCPSIVARSNFNVCRLPGTPEAICATYTGCIIIPGATCPGDYAN

Structure prediction. TTCCPSIVARSNFNVCRLPGTPEAICATYTGCIIIPGATCPGDYAN. At present, there is still no method available that can consistently predict correct structure from a general sequence. Homology Modeling. If the sequence identity between two sequences A and B is greater than 25%,

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Protein structure prediction.

Protein structure prediction. Protein folds. Fold definition: two folds are similar if they have a similar arrangement of SSEs (architecture) and connectivity (topology). Sometimes a few SSEs may be missing.

616 views • 27 slides

Tutorial Homology Modelling

Tutorial Homology Modelling. A Brief Introduction to Homology Modeling. Sequence-Structure-Function Relationships. Proteins of similar sequences fold into similar structures and perform similar biological functions.

1.15k views • 26 slides

Homology Modeling

409 views • 22 slides

MolIDE2: Homology Modeling Of Protein Oligomers And Complexes

MolIDE2: Homology Modeling Of Protein Oligomers And Complexes. Qiang Wang, Qifang Xu, Guoli Wang, and Roland L. Dunbrack, Jr. Fox Chase Cancer Center Philadelphia, PA 19111. Agenda. Background MolIDE in retrospect MolIDE2 Demonstration Discussion.

362 views • 22 slides

Protein Folding Programs

Protein Folding Programs. By As?m OKUR CSE 549 November 14, 2002. Protein Structure. DNA Sequence ? Protein Sequence ? Structure ? (Mis)function It is believed that all the information necessary to determine the structure of a protein is present in its primary sequence.

306 views • 19 slides

Protein Structure Prediction

Protein Structure Prediction. Reporter: Chia-Chang Wang Date: April 1, 2005. Introduction. Why do we need protein structure prediction ? X-ray Crystallography, Nuclear Magnetic Resource(NMR) and Molecular Dynamics(MD)

578 views • 18 slides

In Silico Protein Behavior

In Silico Protein Behavior. Predicting the Activity of p53 Tumor Suppressor Protein Mutants Using Features Derived From Homology Modeling. Sam Danziger Department of Biomedical Engineering University of California, Irvine. Dr. Rainer Brachmann School of Medicine. Dr. Richard Lathrop

269 views • 14 slides

Homology modeling of G protein-coupled receptors

Homology modeling of G protein-coupled receptors. Aug 24~26, 2009 ? 3 ? ??? ?? ???. Eo, Hae-Seok. School of Computational Sciences, KIAS. G protein-coupled receptors (1). Cell surface. G protein-coupled receptors (GPCRs) Transmembrane proteins

477 views • 9 slides

Homology modeling with SWISS-MODEL

Homology modeling with SWISS-MODEL. Building of hER-beta in agonist conformation Robert Dilis. Homology Modeling. Homology modeling allows to build the structure of a protein when only its amino acid sequence and the complete atomic structure of at least one other reference protein is known

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P9 Extra Discussion Slides

P9 Extra Discussion Slides. Sequence-Structure-Function Relationships. Proteins of similar sequences fold into similar structures and perform similar biological functions. The protein sequence has the intrinsic information to encode the protein structure.

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Workshop on Biological Macromolecular Structure Models

Topic 3: Structural Genomics and Models Contributors: S.K. Burley, A. Fiser, A. Godzik, A. Joachimiak, J. Markley, G. Montelione, C. Orengo, A. Sali, and M. Sauder Discussion Leader: Stephen K. Burley. Workshop on Biological Macromolecular Structure Models

162 views • 8 slides

Current Status of Homology Modeling Using MCSG Structures

1t5b domain. 1t5b domain. Q92LV5. Q92LV5. template. template. domain model. domain model. Gly140/141. Gly140/141. Gly140/141. Gly140/141. Gly154/155. Gly154/155. Gly154/155. Gly154/155. Tyr95. Tyr95. Tyr95. Tyr95. Phe97. Phe97. Phe97. Phe97. Phe103. Phe103. Phe103.

127 views • 7 slides

BTY516: Protein Engineering

BTY516: Protein Engineering . Lecture Plan . Protein : introduction Basic mechanism of protein folding pathways, stability and function. Sequence analysis and peptide synthesis Protein structure information Protein structure prediction X-ray and NMR based - Basics

275 views • 2 slides