Formulation design - PowerPoint PPT Presentation

Production/Formulation, Design, Process Development and Pilot-Scale Testings A. Preformulation 1 . Background Informat

Production/Formulation, Design, Process Development and Pilot-Scale Testings A. Preformulation 1 . Background Information 2. Bulk Characterization 3. Solubility Analysis 4. Stability and Compatibility B. Formulation Studies 1. Formulation Design and Trial Manufacturing

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2. Design in Pharmaceutical Product Development

2. Design in Pharmaceutical Product Development. Design &amp; Selection of Drug Substance. High Failure Rate . For every 10,000 NCE’s in Discovery 10 enter pre-clinical development 5 enter human trials 1 is approved Interestingly….. Winning the lottery 1 in 5,200,000

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Therapeutic activity of medicinal substances caused by :

Lecture 2 “Influence of pharmaceutical factors, such as physical state, simple chemical modification of medicinal substance on the therapeutic efficiency of medicines ”.

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354 views • 17 slides

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