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Environmental signal integration by a modular AND gate

Environmental signal integration by a modular AND gate. J Christopher Anderson, Christopher A Voigt and Adam P Arkin. Presented by: Pei-Ann Lin and Jessica Perez. Genetic Circuit Design. Coupling environmental signal(s) to new functions

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276 views • 17 slides

HIF-2 ?

Figure S1. parp-1 +/+. parp-1 -/-. H. N. H. N. HIF-2 ?. DAPI.

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139 views • 3 slides

Time (h)

-P-EGFR. -P-ERK1/2. -P-p90 rsk. -P-CREB. -Tubulin. 0 5 10 15 30 60 EGF (100ng/ml) min. 25. A. B. 20. 15. Fold Induction (EGF/Control). 10. 5. 0. 0 1 2 3 4 5 6. -5. Time (h). EGF. EGF+U0126. C. D.

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141 views • 1 slides

1 72

A. 1 72. B. HCT-15. **. *. *. n-fold induction of KCDT11 mRNA. AZA. CTR. HCT-116. **. n-fold induction of KCDT11 mRNA. CTR. AZA. C. 72. 70. 71. 65. 66. 67. 68. 69. 61. 62. 63. 64. 58. 59. 60.

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135 views • 1 slides

Time (Hours)

B. ABCA1. ABCG1. A. 40. 10. *. *. 7. 9. 35. ABCA1. 8. 6. 30. *. ABCG1. 7. *. 5. *. Fold Induction. Fold Induction. *. 25. 6. *. *. Fold Induction. 4. *. 20. 5. *. *. 4. 3. 15. 3. 10. 2. 2. 5. 1. 1. 0. 0. T0. GW. 623. VEH. VEH. 0. VEH.

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128 views • 1 slides

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Fold induction - PowerPoint PPT Presentation

Environmental signal integration by a modular AND gate

HIF-2 ?

Time (h)

1 72

Time (Hours)