'Dose escalation' presentation slideshows

Accidents D uring Clinical Trials

3.02k views • 79 slides

J Paul Seale MD, FAAFP Daniel P. Alford, MD, MPH, FACP, FASAM H E Woodall MD FAAFP, FAAHPM

An SBIRT Approach to Managing Pain & Prescription Opioid Abuse: Maximizing Benefits and Minimizing Risks. J Paul Seale MD, FAAFP Daniel P. Alford, MD, MPH, FACP, FASAM H E Woodall MD FAAFP, FAAHPM November 2, 2011. Module 1: Initial Assessment & Baseline Measurement. J Paul Seale MD, FAAFP

895 views • 74 slides

Radioisotopes in diagnostics and therapy (pre-)clinical view

Radioisotopes in diagnostics and therapy (pre-)clinical view. Otto C. Boerman. Radboud University Nijmegen Medical Center, The Netherlands. Radioisotopes in diagnostics and therapy. Radioimmunotherapy of cancer Radioimmunoscintigraphy Pretargeted imaging of cancer

880 views • 70 slides

Inrathecal Drug Delivery What have we learned ?

604 views • 49 slides

7 th July CRH talk

7 th July CRH talk. Dr George Hruby Senior Staff Specialist Sydney Cancer Centre. Outline of Talk. IGRT (Image Guided Radiation Treatment) as applied to prostate cancer Update the Sydney Cancer Centre HDR (high dose rate) brachytherapy programme. Introduction.

617 views • 46 slides

602 views • 37 slides

Sense and nonsense of high-dose cytarabine for acute myeloid leukemia

Sense and nonsense of high-dose cytarabine for acute myeloid leukemia . Dr.zavar Hematology resident Mofid pediatric hospital 1392/5/14. Contents. 1. Early studies that have established the use of HDAC in first-line treatment

538 views • 36 slides

Prostate Support Group

Prostate Support Group. Dr Duncan McLaren Consultant Oncologist. Presentation. Radiotherapy results Current RT dose IGRT IMRT- Rapid arc HDR Q&A session New Drugs Q&A. Some good news. 80%. 2001-6. 70%. 1996-01.

446 views • 34 slides

GSK1120212

Safety and Efficacy Results from the First-Time-in-Human Study of the Oral MEK 1/2 Inhibitor GSK1120212.

430 views • 30 slides

Robert N. Baldassano, MD Colman Professor of Pediatrics

What do we do when the patient loses their response to an anti-TNF: Minor tweaks or major treatment changes?. Robert N. Baldassano, MD Colman Professor of Pediatrics University of Pennsylvania, Perelman School of Medicine Director, Center for Pediatric IBD

409 views • 29 slides

Bayesian Adaptive Methods

Bayesian Adaptive Methods. Carrie Deis Nadine Dewdney. Overview. Phase I clinical trials Standard Designs Adaptive Designs Bayesian Approach Traditional vs. Bayesian Hybridization FDA Guidance Conclusion. Phase I. Conducted to determine toxicity for the dosing of the new intervention

543 views • 27 slides

Abstract #3005

First-in-man Phase I study of the oral dual PI3K and mTORC1/2 inhibitor BEZ235 in patients with advanced solid tumors. Howard Burris 1 , Jordi Rodon 2 , Sunil Sharma 3 , Roy Herbst 4 , Josep Tabernero 2 , Jeffrey Infante 1 , Antonio Silva 5 , David Demanse 5 , Wolfgang Hackl 5 , Jose Baselga 2

323 views • 26 slides

When Should We Stop Anti-TNF Therapy and How Do We Then Treat the Patient?

356 views • 24 slides

423 views • 23 slides

21th WCC, Shenzhen, China, Aug 19, 2010 Guo-Liang Jiang, MD, FACR Min Fan, MD, Jiayan Chen, MD

Combination of radiation therapy and Gefitinib for non-small cell lung carcinoma. 21th WCC, Shenzhen, China, Aug 19, 2010 Guo-Liang Jiang, MD, FACR Min Fan, MD, Jiayan Chen, MD Fudan University Shanghai Cancer Center. Outcome of non-small cell carcinoma.

307 views • 20 slides

Bruce Minsky

278 views • 13 slides

100

400. 4. 350. 300. 3. 250. 200. 2. 150. 100. 1. 50. 0. 0. 0. 5. 10. 15. 20. 25. 30. 35. 40. Time (hours). Plasma Concentration. UMSS.

115 views • 1 slides

162 views • 1 slides

Starting Oral Morphine

Starting Oral Morphine. If pain is uncontrolled on WHO step 2 analgesics at full dose (e.g. codeine 60mg qds ). Either. Or. Titration with m/r morphine. Titration with i/r morphine. NB: Use lower starting doses in elderly, frail or renal impairment

211 views • 1 slides

Starting Oral Morphine

Starting Oral Morphine. If pain is uncontrolled on WHO step 2 analgesics at full dose (e.g. codeine 60mg qds ). Either. Or. Titration with m/r morphine. Titration with i/r morphine. NB: Use lower starting doses in elderly, frail or renal impairment

157 views • 1 slides