'Ctla 4' presentation slideshows

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???? ????. ? ? ? ? ? immune regulation ?. ??????? , ?????????????????? , ??????????? , ?????????? , ???????????????????????????????? ?? ? 1. ??????????????? 2. ?????????? ????????. ?????????. ????? MHC ???? MHC ?? ??????????? IC ???????????? ????? APC ??? T/B ??? NK ??

1.15k views • 100 slides

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?????????. ???????????? ????????????????????????????????????????????? , ????????????????????????????????????????. Immune regulation. The ability of the immune system to sense and regulate its own responses. ????? ?????????? ?????????????????

941 views • 69 slides

???? ? Immunoregulation ?

???? ? Immunoregulation ?. ??? ?????????? Lu.Linrong@gmail.com. Immunoregulation. The ability of the immune system to sense and regulate its own responses: 1. To determine the type and scale of a response; 2. To ensure Fast Response upon exogenous antigen stimulation;

1.35k views • 69 slides

Chapter 10 Immunologic Tolerance

Chapter 10 Immunologic Tolerance. General Features and Mechanisms T Lymphocyte Tolerance B Lymphocyte Tolerance Tolerance induced by Foreign Protein Antigens Homeostasis in the Immune System. What is Immunologic Tolerance?.

1.47k views • 67 slides

t-cellbiology/teaching

Simon Davis, Ed Evans: ? 21336. www.t-cellbiology.org/teaching. Methods Course, November 4th. 1. Expression cloning In bacteria In mammalian cells Yeast 2-hybrid screens. N.B. Now rarely used!. Methods Course, November 4th. 2. Protein expression (overview) Why express proteins at all?

774 views • 57 slides

Chapter 5

Chapter 5. Cell-Mediated Immune Response. Cell-Mediated Purpose. Combat infection of intracellular microbes virally infected cells have virus replicating inside the cytoplasm phagocytes that pick up microbes but they are resistant to destruction, grow in vesicles or cytoplasm

687 views • 52 slides

T-Cell Maturation, Activation, And Differentiation

T-Cell Maturation, Activation, And Differentiation. W. Robert Fleischmann, Ph.D. Department of Urologic Surgery University of Minnesota Medical School rfleisch@umn.edu (612) 626-5034. Objectives. To understand T cell maturation in the thymus, including positive and negative selection

4.89k views • 44 slides

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CD. ????????. ??? ??????. HLDA/CD ?? HLDA8 ??? CD ?? ?? CD ????????? trafficking ????? CD4 + T ???? IgSF ???????????? Siglec ?? CD226 ???? HLDA9. ???? ( ????? ). ?? Ag. ?? ??. + MHC. ??? ? ?. Ag Ig ???? ????. ???? ????. TNF SF. IgFc ??. ?? ??. ?? NK

847 views • 40 slides

Immunotherapy for Prostate Cancer: Are we on the right target?

Immunotherapy for Prostate Cancer: Are we on the right target?. Susan F. Slovin, MD, PhD Sidney Kimmel Center for Prostate and Urologic Cancers Memorial Sloan-Kettering Cancer Center New York, New York. Rationale for Vaccines in Prostate Cancer.

742 views • 38 slides

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509 views • 38 slides

T-Cell Maturation, Activation, And Differentiation

T-Cell Maturation, Activation, And Differentiation. W. Robert Fleischmann, Ph.D. Department of Urologic Surgery University of Minnesota Medical School rfleisch@umn.edu (612) 626-5034. Objectives. To understand T cell maturation in the thymus, including positive and negative selection

846 views • 35 slides

Immunresponsen

507 views • 33 slides

Immunotherapy for Cancer

Immunotherapy for Cancer. Success At Last! Russell M. Eldridge MD. What is Immunotherapy, and why is everyone talking about it?. An old idea finally delivers the biggest breakthrough in cancer treatment in the last 30 years. Brief History of Cancer Treatments. Surgery is the oldest

621 views • 30 slides

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????. ????. ? . T ????. T ????????? T ??????? T ????????????. ??? T ??????. 1. TCR (T cell receptor):. T ??????. TCR ?? TCR ??. ? ??? ????. ??? T ??? 90% ??? T ?. V ? ? V ? ?? TCR ???. ????? 1-6 ? aa ??????. 2. TCR-CD3 ???. ??? + ?????. CD 3 ????. ? ?????

611 views • 26 slides

Topics

Statistical Adaptation to Oncology Drug Development Evolution: From Cut/Burn/Poison to Immunotherapy Mingxiu Hu, PhD, ASA Fellow Sr. Vice President, Data Science and Systems Adjunct Professor of Biostatistics , Yale University 3 rd OncoStat Symposium, April 26-27, 2019. Topics.

689 views • 25 slides

The B7/CD28 pathway is much more complicated than expected

The B7/CD28 pathway is much more complicated than expected. Chambers C.A. et al. Immuunol. Rev. 153:27, 1996. B7/CD28/CTLA-4. Activated T cell. AP2. AP2. TCR. CTLA-4. CD28. P. P. peptide/ MHC. B7.1 (CD80). Activated Professional APC. B7.2 (CD86).

398 views • 24 slides

PLC activation Ca++ flux NF-AT / NFkB nuclear localization protein tyrosine phosphorylation

332 views • 22 slides

731ES13PR06651-01

348 views • 22 slides

NEGATIVE REGULATION OF THE IMMUNE SYSTEM

NEGATIVE REGULATION OF THE IMMUNE SYSTEM. NEGATIVE REGULATION IN THE IMMUNE SYSTEM Decrease of antigen concentration in the course of the immune response Inhibition of B lymphocyte activation - antibody feedback Cross linking of BCR with Fc ? RIIB (CD32) by antigen-antibody complex

324 views • 15 slides

Immune System Project : CD28

Immune System Project : CD28. BY: Wells Powell & Tamia Johnson.

139 views • 6 slides