'Classical pathway' presentation slideshows

The Complement System

1.66k views • 119 slides

Chapter 6 Complement

Chapter 6 Complement. The end of 19 century Jules Bordet (1870-1961). Fresh serum containing an antibacterial antibody was added to the bacteria at physiologic temperature (37 ? ?? bacteria were lysed. If the serum was heated to 56 ? or more , it lost its lytic capacity.

1.28k views • 109 slides

The Complement System

The Complement System. Adapted from the Presentation of Jean F. Regal, Ph.D. Medical School - Duluth. Learning Objectives. Explain the importance of the complement system in host defense and inflammation and the clinical consequences of complement deficiencies.

1.27k views • 77 slides

Fire Ant Stings and Other Mishaps: Immnology

Fire Ant Stings and Other Mishaps: Immnology. Donna Sullivan, PhD. Host Defensive Systems. 1st line of defense - intact skin mucous membranes and their secretions 2nd line of defense - phagocytic white blood cells inflammation -complement fever -interferon 3rd line of defense-

893 views • 62 slides

Probabilistic Approximations of ODEs Based Signaling Pathways Dynamics

Probabilistic Approximations of ODEs Based Signaling Pathways Dynamics. P.S. Thiagarajan School of Computing, National University of Singapore. A Common Modeling Approach. View a pathway as a network of bio-chemical reactions Model the network as a system of ODEs

561 views • 44 slides

Innate immunity is germline encode (you are born with it ready to go) It has made the self/nonself discrimination on an

revised: 9/27/04 AM. Chapter 2: Innate Immunity. Innate immunity is germline encode (you are born with it ready to go) It has made the self/nonself discrimination on an evolutionary time-scale It uses few receptors that recognize features common to many microorganisms

766 views • 43 slides

THE COMPLEMENT SYSTEM

THE COMPLEMENT SYSTEM. THE COMPLEMENT SYSTEM. The complement system is a set of plasma proteins that act in a cascade to attack and kill extracellular pathogens . Approximately 30 components : activating molecules regulator factors complement receptors

815 views • 43 slides

Dr. M. Izad Sep 2014

The Complement System. Dr. M. Izad Sep 2014. To understand how the complement system works To determine the Role of Complement in the Innate & Acquired Immunity Regulation of complement system To understand the consequences of Deficiency of Complement. Objectives. History.

545 views • 40 slides

The complement system

The complement system. Complement functions in two (three?) systems: Alternative Classical Lectin-based. Complement has three functions: Opsonin Chemoattractant Membrane Attack Complex (MAC). The complement system.

613 views • 40 slides

Complement

713 views • 38 slides

Aims

Aims. Describe the activation of the complement cascade via: Classical pathway Alternative pathway Explain how activation of the complement cascade can impact other immunologic processes. Describe clinical implications of complement deficiencies. Readings: Abbas & Lichtman, Chapter 8.

572 views • 38 slides

Group A Streptococcus: Host Aspect Yee-Shin Lin, Ph.D. December 19, 2007

INFECTIOUS DISEASES. Group A Streptococcus: Host Aspect Yee-Shin Lin, Ph.D. December 19, 2007. Outlines Introduction Pathogenesis and host responses Host-streptococcus interactions Innate immune responses Induction of inflammation and apoptosis

481 views • 35 slides

Innate Immunity: Nonspecific Defenses of the Host

16. Innate Immunity: Nonspecific Defenses of the Host. TERMINOLOGY. Susceptibility: Lack of resistance to a disease. Immunity: Ability to ward off disease. Innate immunity: Defenses against any pathogen. Adaptive immunity: Immunity, resistance to a specific pathogen.

684 views • 29 slides

Nonspecific Defenses of the Host

Nonspecific Defenses of the Host. Susceptibility: Lack of resistance to a disease. Immunity: Ability to ward off disease. Innate immunity: Defenses against any pathogen. Adaptive immunity: Immunity, resistance to a specific pathogen. Host Defenses. Figure 16.1. Physical Factors. Skin

483 views • 29 slides

Unit 1 Nature of the Immune System Part 9 Complement

Unit 1 Nature of the Immune System Part 9 Complement. Terry Kotrla, MS, MT(ASCP)BB. Introduction. Complement refers to a complex set of 14 distinct serum proteins (nine components) that are involved in three separate pathways of activation. Components numbered in order of discovery.

415 views • 25 slides

COMPLEMENT SYSTEM

COMPLEMENT SYSTEM. By Dr. Marwa Salah. Learning objectives. 1. Name the complement pathways. 2. How is complement system activated? Why is it effective against microbes but does not react against host cells and tissues?

2.18k views • 23 slides

Complement

340 views • 20 slides

Complement System

339 views • 18 slides

546 views • 16 slides

Complement system

Complement system. main humoral mechani s m of nonspecific immunity - > 40 glykoprot eins - blood - on the surface of immune cells

690 views • 13 slides