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Cellular prion protein - PowerPoint PPT Presentation

Chapter 10 Viruses

Chapter 10 Viruses

Chapter 10 Viruses. Viruses contain DNA or RNA And a protein coat called a The capsid is composed of individual Some are enclosed by an envelope May have spikes protruding from envelope . Most viruses infect only specific types of cells in one host

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Useful Terms & Abbreviations

Useful Terms & Abbreviations

Acidic pH and Detergents Enhance in Vitro Conversion of Human Brain PrP c to a PrP Sc -like Form by Wen-Quan Zou and Neil R. Cashman The Journal of Biological Chemistry Vol. 277, No. 46, Issue of November 15, pp. 43953-43947, 2002. Useful Terms & Abbreviations.

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Spongiform Encephalopathies ( TSEs)

Spongiform Encephalopathies ( TSEs)

Spongiform Encephalopathies ( TSEs). Transmissible spongiform encephalopathies. Transmissible spongiform encephalopathies (TSEs) are a family of diseases of humans and animals. They are transmitted by prions , but other suggest an involvement of a Spiroplasma infection.

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Detection of prions by analytical methods.

Detection of prions by analytical methods.

Detection of prions by analytical methods. Osman Adil Jamshed Chem 4101 9th December, 2011. Reference: Prion structure, http://www.uccs.edu/~rmelamed/MicroFall2002/Chapter%2010/Prion%20Structure.html (accessed Oct 25 2011) . PrP C. PrP Sc. Prions.

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From BSE t o Prion

From BSE t o Prion

From BSE t o Prion. Prion: An infectious proteinaceous particle of nonnucleic acid composition. Bovine spongiform encephalopathy (BSE ) mad-cow diseas e. Prion protein (PrP) : from PrP C to PrP S c. Same amino acid sequences but different structures. PrP S c (scrapie prion protein)

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