'Cell activation' presentation slideshows

Immunoglobulins: s tructure and f unction

Immunoglobulins: s tructure and f unction. Immunoglobulins. Definition : Glycoprotein molecules that are present on B cells (BCR) or produced by plasma cells (antibodies) in response to an immunogen. Immunoglobulin Structure. h eavy and l ight c hains d isulfide bonds

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PATHOPHYSIOLOGY OF SELECTED AUTOIMMUNE DISEASES

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Lymphocyte Activation & Immune Tolerance

Lymphocyte Activation & Immune Tolerance. Pin Ling ( ? ? ), Ph.D. ext 5632; lingpin@mail.ncku.edu.tw References: 1. Abbas, A, K. et.al, Cellular and Molecular Immunology (6th ed., 2007), Chapter 9-11. Question. What is happened to the immune system if RAG1 & RAG2 are mutated?.

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Cytokines and Thelper subsets

Cytokines and Thelper subsets. MCB 150, Pr Coscoy. I. Characteristics of Cytokines (CKs) . CKs are small proteins (<30 kDa) CKs are similar to hormones and growth factors. CKs control the immune system. Cytokines include subsets called lymphokines, monokines, chemokines, etc.

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Sequential expression of membrane Ig

Sequential expression of membrane Ig Surrogate light chain consists of 2 proteins: a V-like protein and a C-like protein. B cells undergo negative selection. Negative selection: Clonal deletion of cells that express antibodies against self antigens. Two routes for B cell activation

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New Treatments for Rheumatoid Arthritis

PHM142 Fall 2013 Coordinator: Dr. Jeffrey Henderson Instructor: Dr. David Hampson. New Treatments for Rheumatoid Arthritis. Presented by: Ariel Kwan Christine Terzievski Rebecca Babaei-Rad Vivian Tsoi. Course: Biochem PHM142 Presented on: Oct 23, 2013.

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Cell Mediated Immunity (CMI)

Cell Mediated Immunity (CMI). Prof. Dr. Zahid Shakoor MBBS, Ph D (London) College of Medicine King Saud University. Antigen. T-lymphocytes. Immune responses. Cell-Mediated Immunity (CMI). Cell Mediated Immunity. Cell-mediated immunity ( CMI ).

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T lymphocytes

T lymphocytes. Contents. 1. Surface markers on T lymphocytes and their function 2. Subsets of T lymphocytes 3. Function of T lymphocytes.

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T Cell Activation

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Lymphocyte Interactions

Lymphocyte Interactions. Both the activation and functions of lymphocytes require them to interact with each other and with other cell types .

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Immuno and Epigenetic Therapies

Immuno and Epigenetic Therapies. Xiaole Shirley Liu STAT115, STAT215, BIO298, BIST520. Cancer Immunology. Would tumor grow in another individual?. Effector Lympocytes. Lymphocytes express highly specific ANTIGEN RECEPTORS on their surface

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Antigens

Antigens. Jennifer Nyland, PhD Office: Bldg#1, Room B10 Phone: 733-1586 Email: jnyland@uscmed.sc.edu. Teaching objectives. To compare and contrast immunogen , antigen & hapten To describe the factors influencing immunogenicity To define the chemical nature of immunogens

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Eugene P. Mayer

Eugene P. Mayer. Office: Bldg. #2, Rm. B19 Phone: 733-3281 Email: MAYER@MED.SC.EDU. Overview of the Immune System. Antigens. Definitions. Immunogen Antigen (Ag) Hapten Epitope or Antigenic Determinant Antibody (Ab) . Sequence determinants. Conformational determinants.

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Eugene P. Mayer

Eugene P. Mayer. Office: Bldg. #2, Rm. B19 Phone: 733-3281 Email: MAYER@MED.SC.EDU. Overview of the Immune System. Antigens. Definitions. Immunogen Antigen (Ag) Hapten Epitope or Antigenic Determinant Antibody (Ab) . Factors Influencing Immunogenicity Contribution of the Immunogen.

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Ischemic Heart Disease

Ischemic Heart Disease. Group of diseases Most common cause of death in developed countries Terminology: Angina pectoris Myocardial infarction Sudden cardiac death Chronic ischemic heart disease Coronary artery disease Acute coronary disease. Ischemic Heart Disease.

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Biology of the B lymphocyte

Biology of the B lymphocyte. Figure 7.1 Differentiation pathway of B lymphocytes. Dashed lines on the pre-B cell indicate surrogate light chains. The two lines associated with the cell surface heavy chain represent the molecules Iga and Igb. Overview of B cell development.

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The Antitumor Immune Response

The Antitumor Immune Response. Structures of Class I and Class II Major Histocompatability Complex (MHC) Molecules. With permission from Abbas et al. Cellular and Molecular Immunology . 1994. Pathway of Antigen Presentation by Antigen-Presenting Cells.

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T-cell activation positively correlates with cell-associated

T-cell activation positively correlates with cell-associated HIV-DNA level in PBMCs in viremic patients with acute or chronic HIV-1 infection.

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T-cell activation positively correlates with cell-associated

T-cell activation positively correlates with cell-associated HIV-DNA level in PBMCs in viremic patients with acute or chronic HIV-1 infection.

114 views • 1 slides