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Bone Neoplasm

Bone Neoplasm. Bone Neoplasm. Benign – Malignant differentiation Location Margins of lesion Sharp = narrow zone of transition = not aggressive Fuzzy = wide zone of transition = aggressive Matrix – appearance of contents Chondroid – cartilage like Osteoid – bone like Mixed.

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Bone Neoplasm

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  1. Bone Neoplasm

  2. Bone Neoplasm • Benign – Malignant differentiation • Location • Margins of lesion • Sharp = narrow zone of transition = not aggressive • Fuzzy = wide zone of transition = aggressive • Matrix – appearance of contents • Chondroid – cartilage like • Osteoid – bone like • Mixed

  3. Non-ossifying Fibroma • Well defined sclerotic margin • Internal septations

  4. Non Ossifying Fibroma • Sharp demarcation • Benign appearing

  5. Enchondroma Phalanx • Sharp margins • Typical location • Benign process

  6. Osteogenic Sarcoma • Destructive lesion in the distal femur (arrowheads) • Permeative – ‘broad zone of transition’ • Extends into the medial soft tissues • Zone of periosteal reaction along proximal femur (arrows)

  7. ParostealOsteogenic Sarcoma

  8. Metastatic Breast Cancer • Destructive lesion of the proximal humerus • History of breast carcinoma

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