agonists and antagonists l.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Agonists and Antagonists PowerPoint Presentation
Download Presentation
Agonists and Antagonists

Loading in 2 Seconds...

play fullscreen
1 / 2

Agonists and Antagonists - PowerPoint PPT Presentation


  • 236 Views
  • Uploaded on

Agonists and Antagonists. Agonists interact with receptors to produce the same cellular effect that is seen with the naturally occurring binding chemicals (ligands) eg salbutamol (eg Ventolin) – agonist at beta 2 receptors; stimulation results in smooth muscle relaxation

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Agonists and Antagonists' - sandra_john


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
agonists and antagonists
Agonists and Antagonists
  • Agonists interact with receptors to produce the same cellular effect that is seen with the naturally occurring binding chemicals (ligands)
    • eg salbutamol (eg Ventolin) – agonist at beta2 receptors; stimulation results in smooth muscle relaxation
  • Antagonists interact with receptors and block the effects of the naturally occurring ligands
    • eg ranitidine (eg Zantac) – antagonist at histamine H2 receptors; blockade reduces acid secretion in the stomach
problems with relying on acid secretion as sole mechanism of peptic ulcer healing
Problems with relying on acid secretion as sole mechanism of peptic ulcer healing
  • Treatment has to be continuous. After cessation of therapy acid secretion quickly rises and ulcer recurrence rates are high (70% in 12 months for duodenal ulcers)
  • Inhibition of acid secretion does not eradicate H Pylori
  • However acid secretionis valuable in the healing and prevention of ulcers due to NSAIDs