intro. Persons in a population respond to diseases differently due to the phenotypic variations of resistance. It is proposed that inheritance factors play a major role in mortality rates.
PowerPoint Slideshow about 'intro' - sailor
An Image/Link below is provided (as is) to download presentation
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
R. May and R. Anderson, Infectious Disease in Humans (Oxford Univ. Press, New York, 1995).
S. S. Morse, Ed., Emerging Viruses (Rockefeller Univ. Press, New York, 1993).
T. I. A. Sorensen, G. G. Nielsen, P. K. Andersen, T. W. Teasdale, N. Engl. J. Med.318, 727 (1988) .
A. G. Motulsky, Human Genetics: Patterns and Approaches (Springer-Verlag, Berlin, 1981).
S. Wain-Hobson, Curr. Opin. Genet. Dev.3, 878 (1993) [Medline].
J. M. Coffin, Science267, 483 (1995) [Medline].
E. L. Delwart et al., ibid.262, 1257 (1993) [Medline].
R. A. Kaslow et al., Nature Med.2, 405 (1996) [Medline]; B. F. Haynes, G. Pantaleo, A. S. Fauci, Science271, 324 (1996) [Medline].
W. A. Paxton et al., Nature Med.2, 412 (1996) [Medline]; R. Detels et al., AIDS10, 102 (1996) .
F. Cocchi et al., Science270, 1811 (1995) [Medline]; M. Baier, A. Werner, N. Bannert, K. Metzner, R. Kurth, Nature378, 563 (1995) [Medline].
Y. Feng, C. C. Broder, P. E. Kennedy, E. A. Berger, Science272, 872 (1996) [Medline].
B. Federsppiel et al., Genomics16, 707 (1993) [Medline].
H. Herzog, Y. J. Hort, J. Shine, L. A. Selbie, DNA Cell Biol.12, 465 (1993) [Medline].
H. Nomura, B. W. Nielsen, K. Matsushima, Int. Immunol.5, 1239 (1993) [Medline].
P. J. Madden et al., Cell47, 333 (1986) .
C. Combadiere, S. K. Ahuja, H. L. Tiffany, P. M. Murphy, J. Leukocyte Biol.60, 147 (1996) [Medline]; M. Samson, O. Labbe, C. Mollereau, G. Vassart, M. Parmentier, Biochemistry35, 3362 (1996) [Medline].
T. Dragic et al., Nature381, 667 (1996) [Medline].
G. Alkhatib et al., Science272, 1955 (1996) [Medline].
H. Choe et al., Cell85, 1135 (1996) [Medline].
B. J. Doranz et al., ibid., p. 1149.
H. Deng et al., Nature381, 661 (1996) [Medline].
P. M. Murphy, Annu. Rev. Immunol.12, 593 (1994) [Medline].
K. Neote, D. DiGregorio, J. Y. Mak, R. Horuk, T. J. Schall, Cell72, 415 (1993) .
C. J. Raport et al., J. Leukocyte Biol.59, 18 (1996) [Medline].
M. A. Walter, D. J. Spillett, P. Thomas, J. Weissenbach, P. Goodfellow, Nature Genet.7, 22 (1994) [Medline].
M. White, M. Carvalho, D. Derse, S. J. O'Brien, M. Dean, Genomics12, 301 (1992) [Medline]; M. Ravnik-Glavac, D. Glavac, M. Dean, Hum. Mol. Genet.3, 801 (1994) [Medline].
M. Orita, Y. Suzuki, T. Sekiua, K. Hayashi, Genomics5, 874 (1989) [Medline].
M. Samson, Nature382, 722 (1996) [Medline].
R. Liu et al., Cell86, 367 (1996) [Medline].
Eight CKR5 variant alleles were found. These include the 32 deletion; a variant that occurred as a heterozygote in 15 individuals of 600 screened by SSCP; four variants found as heterozygous in single individuals that were HIV-1 infected, but had not progressed to AIDS after 7 to 10 years; and two variants in HIV-1-infected individuals that had not been followed for long term as yet. Preliminary sequence analysis revealed missense alterations in codons for conserved amino acids in three of the variants.
M. W. Hilgartner et al., Am. J. Pediatr. Hematol. Oncol.15, 208 (1993) [Medline].