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Photoinduced cytotoxicity

Bilkent Üniversitesi. Photoinduced cytotoxicity.

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Photoinduced cytotoxicity

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  1. Bilkent Üniversitesi Photoinduced cytotoxicity Fluorescence microscope images of acridine orange (AO) and propidium iodide (PI) stained K562 cells, incubated in full medium with 500 nM sensitizer 3 in dark (the middle panel); irradiated with red LED at 625 for 4 hours followed by 20 hr incubation in dark at 37 oC in the presence of 500 nM sensitizer 3 (right panel); and incubated in dark for 24 hr (left panel). Live cells were preferentially stained with AO (green) and dead cells with PI (red) due to increased cellular permeability.

  2. Bilkent University CNT-derivatization

  3. Bilkent University SWCNTs as carries for PDT reagents

  4. Bilkent University SWCNTs as carriers for PDT reagents • AFM image of compound 1-SWNT. (B) AFM 3D topographic view. • PSIA XE-100E AFM and Multi75AI tip was used in noncontact mode with resonance frequency 75 KHz and force constant 3.0 N/m.

  5. Bilkent University SWCNTs as carriers for PDT reagents

  6. PDT reagents with pH-modulated activity Bilkent University dye DPSB 670 nm dye DPSB + H+

  7. Moore’s Law Bilkent University

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