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NHS Tayside. For Use in Specialist Hepatology Clinic Only. 1 DNA ≥ 10 5 copies/ml if HBeAg +, DNA ≥ 10 4 copies/ml if HBeAg – 2 Consider liver biopsy if ALT persistently 1-2xULN 3 If CD4 350-500 consider early initiation of HAART
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NHS Tayside For Use in Specialist Hepatology Clinic Only 1DNA ≥ 105 copies/ml if HBeAg +, DNA ≥ 104 copies/ml if HBeAg – 2Consider liver biopsy if ALT persistently 1-2xULN 3If CD4 350-500 consider early initiation of HAART Nucleosides : lamivudine 100 mg od, adefovir 10 mg od, entecavir 0.5 mg od (1 mg od if lamivudine resistance) (telbivudine not recommended in Tayside) HAART= antiretroviral therapy; TRV = truvada (tenofovir + emtricitabine) 1 tab od