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Group R14300 – Digital Microfluidics

Group R14300 – Digital Microfluidics. Peter Dunning Paulina Klimkiewicz Matthew Partacz Andrew Greeley Thomas Wossner Wunna Kyaw. Motivation. Need for point of care medical testing devices where access to conventional tests is restricted

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Group R14300 – Digital Microfluidics

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  1. Group R14300 – Digital Microfluidics Peter DunningPaulina Klimkiewicz Matthew Partacz Andrew Greeley Thomas Wossner WunnaKyaw

  2. Motivation • Need for point of care medical testing devices where access to conventional tests is restricted • Ex: Doctor’s Offices, Remote Areas, Battlefields • A solution must be portable and cheap http://gdb.voanews.com/6C27D536-9955-4670-91C4-101E2D5A6322_w640_r1_s.jpg

  3. Background • Lab-on-a-chip devices are capable of miniaturizing and automating biological protocols. • Devices suited for commercial use have yet to be developed. http://2.imimg.com/data2/GK/EX/MY-920622/micro-biological-testing-250x250.jpg http://www.lionixbv.nl/technology/technology-microfluidics.html

  4. Microfluidic Platforms Major microfluidic platforms organized by liquid actuation [1]

  5. Digital MicroFluidic devices • Array of electrodes which use the electrowetting effect to manipulate droplets. Cross-section view of Digital Microfluidic device. Dotted line indicates the shape of the meniscus before actuation. Modified from [2] “The electrowetting effect (in air)” [3] “Top view of flow on a ring structure” [3]

  6. Customer Requirements

  7. Customer Requirement Cont.

  8. Outstanding VOC • We will be meeting with Dr. Schertzer in the near future to confirm these requirements. • Questions for Audience • Are our goals for this project clearly defined? • Do you have some understanding of how Digital Microfluidic Devices work?

  9. References • [1] Mark, D., Haeberle, S., Roth, G., Von Stetten, F., and Zengerle, R., 2010, "Microfluidic Lab-on-a-Chip Platforms: Requirements, Characteristics and Applications," Chemical Society Reviews, 39(3), pp. 1153-1182. • [2] Cho, S. K., Moon, H. J., and Kim, C. J., 2003, "Creating, Transporting, Cutting, and Merging Liquid Droplets by Electrowetting-Based Actuation for Digital Microfluidic Circuits," Journal of Microelectromechanical Systems, 12(1), pp. 70-80. • [3] Fair, R., The Electrowetting Effect (in Air), February 1, http://microfluidics.ee.duke.edu/

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