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Epithelium

Epithelium. Michael Hall PhD. University of California Los Angeles. Features common to all epithelia The cells are closely packed together The cells are polarized The apex always faces an open space The base always sits on a basement membrane. Epithelial cells are closely packed.

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Epithelium

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  1. Epithelium Michael Hall PhD University of California Los Angeles

  2. Features common to all epithelia • The cells are closely packed together • The cells are polarized • The apex always faces an open space • The base always sits on a basement membrane

  3. Epithelial cells are closely packed

  4. Epithelial cells always have a free surface and sit on a basement membrane Free Surface Lamina propria

  5. Epithelium Basement membrane Note that both of the epithelia face a free surface Basement membrane Epithelium

  6. Types of Epithelium Simple One cell layer Stratified More than one cell layer

  7. Types of Epithelium • Simple squamous • Simple cuboidal • Simple columnar • Stratified squamous • Stratified cuboidal • Stratified columnar • Pseudostratified • Transitional

  8. Simple squamous epithelium Free space Basement membrane Connective tissue

  9. Simple squamous epithelium (endothelium) lining an arteriole endothelium

  10. Simple cuboidal epithelium (kidney) Basement membranes Free surface

  11. Simple epithelia in kidney medulla scu ssq scu* ssq scu ssq scu

  12. Simple columnar epithelium (duodenum)

  13. Stratified Squamous Epithelium (cornea) free surface bm ct

  14. Stratified Squamous Epithelium free surface squamous cells basement membrane

  15. Stratified Cuboidal Epithelium Connective tissue Duct of sweat gland Basement membrane

  16. Stratified Columnar Epithelium (urethra) lp bm Columnar cells

  17. Pseudostratified Epithelium

  18. Pseudostratified Columnar Epithelium (duodenum) Basal cells Basement Membrane

  19. Transitional Epithelium (Urinary system)

  20. Transitional Epithelium (relaxed -top layer of cells is cuboidal) basement membrane Transitional Epithelium (stretched-top layer of cells is squamous) basement membrane

  21. Mesothelium Mesothelium is the name given to the simple squamous epithelium that lines the closed cavities of the body endothelium Endothelium

  22. Basement membranes

  23. Simple squamous epithelium Basement membrane Connective tissue

  24. Basement Membrane of epithelium

  25. Molecular structure of extracellular matrix forming the basement membrane Inside of cell

  26. Junctional Complexes

  27. ‘Terminal Bars’ between epithelial cells

  28. Epithelial Junctional Complex Z. occludens Z. adherens Cell 2 Cell 1 Desmosome

  29. Components of the Epithelial Junctional Complex 1 2 • Z. occludens • Z. adherens • Macula adherens • (desmosome) • 4. Gap junction • 5. Hemidesmosome 3 4 5

  30. Cell 1 Cell 2 Generalized Structure of a Junctional Complex

  31. Connexon 2 Connexon 1 Gap Junction < 1,500 Da > 1,500 Da

  32. Surface Specializations of Epithelial Cells

  33. Villin Structure of a microvillus Actin Fimbrin Myosin Spectrin

  34. Stereocilia in the Epididymis Stereocilia

  35. Cilia in the Respiratory Mucosa Cilia

  36. cilia microvilli

  37. Components of a Mucosa Basement membrane Mucosa

  38. The End Whoopee !!

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