How does influenza virus jump from animals to humans?. Haixu Tang School of Informatics and Computing Indiana University, Bloomington. Swine flu outbreak, 2009. Influenza pandemics in human history. Spanish flu, 1918 Most deadly natural disaster Asian flu, 1957 Hong Kong flu, 1968
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School of Informatics and Computing
Indiana University, Bloomington
The glycan motif finding problem
Many 4-treelets appear in ALL input glycan trees.
Glycans are not random!
M glycans printed on the array
N positive, M-N negative
ni+ positives contain the treelet
ni- negatives contain the treelet
Chandrasekaran A, et al. Nat Biotechnol , 2008; 26:107–113.