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Explore the concept of exponential growth in cancer cells through hands-on M&M lab simulation. Learn how cancerous cells divide uncontrollably, contrasting with normal cell division. Includes video analysis of cancer vs. normal cell mitosis.
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January 24, 2013 (Period 5) Agenda: • Review Cell Cycle: Cancer vs. Normal Cells • Mitosis in Cancer Video • Introduction of Exponential Growth • Exponential Growth of Cancer Cells Lab
Learning Objective • SW demonstrate exponential growth in cancerous cells and relate it to cell division.
Cell Cycle Review • Cell Processes and Energy (Fieldtrip)-On Discovery DVD • Answer the following questions: • What are the three stages of the cell cycle? • What is the difference in division rate between cancer cells and normal cells?
Cancer vs. Normal Cell Division On Youtube.com: Mitosis in Cancer- Cancer: Unregulated Cell Division • While watching the short video clip pay attention to the growth rate between cancer and normal cells. • What did you notice between the amount of cancer cells versus animal cells? (Class Discussion)
Exponential Growth • Definition: demonstrates growth at a very fast rate, not constant or steady • Population grows faster by using exponents, instead of adding or multiplying
Exponential Growth and Cancer Cells • So by watching the video of cancer cell and normal cell populations, which cell’s population grows the fastest? • Yes, cancer cell population grows much faster. This is an example of exponential growth.
Modeling Exponential Growth M&M Lab • The purpose of this lab is to provide a simple model to illustrate exponential growth of cancerous cells. In our experiment, an M&M represents a cancerous cell. If the M&M lands “M” up, the cell divides into the “parent” cell and “daughter” cell. The cancerous cells divide like this uncontrollably-without end. • We will conduct up to 10 trials and record the number of “cancerous cells” on the plate.
Exponential Growth • Definition: demonstrates growth at a very fast rate, not constant or steady • Population grows faster by using exponents, instead of adding or multiplying
Rule: **DO NOT EAT THE M&M’s UNTIL YOU ARE DONE COLLECTING ALL DATA**
Exponential Growth Procedure • Place 2 M&M’s in a cup/plate. This is trial number 0. • Shake the cup and dump out the M&Ms. For every M&M with the “M” showing, add another M&M and then record the new population. (Ex. If 5 M&Ms land face up, then you add 5 more M&Ms) • Repeat step number 2 until you are done with 10 trials OR you run out of M&Ms.