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This study evaluates the impact of VEH, FLX, and OLZ on body weight and food intake in rats over the course of restriction days. It analyzes the cumulative survival rates and provides insights into the relationship between drug dosages and physiological changes.
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A VEH 0mg/kg/day FLX 18 mg/kg/day 100 OLZ 12 mg/kg/day 95 90 % Body Weight 85 80 10 11 12 13 14 BL 1 2 3 4 5 6 7 8 9 Day of Restriction B 110 100 90 80 70 % Food Intake 60 50 40 30 20 1 2 3 4 5 6 7 8 9 BL 10 11 12 13 14 Day of Restriction C 1 9, 9 9 8 .8 7 7 6 .6 5 5 Cumulative Survival 4 .4 VEH 0mg/kg/day .2 FLX 18 mg/kg/day OLZ 12 mg/kg/day 0 0 2 4 6 8 10 12 14 16 Day of Restriction