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Study by MR Warden et al. in Nature shows that activating mPFC axons in the DRN induces behavioral activation. This optogenetic approach targets specific neural pathways with precision, shedding light on brain-behavior mechanisms.
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Optogenetic stimulation of mPFC axons in the DRN, but not excitatory mPFC cell bodies, induces behavioural activation. MR Warden et al. Nature492, 482-432 (2012) doi:10.1038/nature11617