conditional inactivation of noggin in the postnatal skeleton causes osteopenia n.
Skip this Video
Loading SlideShow in 5 Seconds..
Conditional inactivation of Noggin in the postnatal skeleton causes osteopenia PowerPoint Presentation
Download Presentation
Conditional inactivation of Noggin in the postnatal skeleton causes osteopenia

play fullscreen
1 / 4
Download Presentation

Conditional inactivation of Noggin in the postnatal skeleton causes osteopenia - PowerPoint PPT Presentation

patia
104 Views
Download Presentation

Conditional inactivation of Noggin in the postnatal skeleton causes osteopenia

- - - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript

  1. Conditional inactivation of Noggin in the postnatal skeleton causes osteopenia Osteoscoop - Issue N°243 – June 2012

  2. Noggin BMP-2 Smad + Sclerostin Osteoblast

  3. Lower weight Shorter femoral length Generalized osteopenia NogginD/+ NogginD/- Noggin BMP-2 Smad + Sclerostin Osteoblast

  4. Lower weight Noggin Low bone formation Wnt signaling BMP-2 Shorter femoral length Smad + Sclerostin Generalized osteopenia Osteoblast NogginD/+ NogginD/-