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TYPE 2 TRANSLATIONAL RESEARCH 2009 GRANT PROGRAMS

TYPE 2 TRANSLATIONAL RESEARCH 2009 GRANT PROGRAMS UW Institute for Clinical and Translational Research (ICTR) Community-Academic Partnership Core (CAP). UW Institute for Clinical and Translational Research. Overall Goal of ICTR

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TYPE 2 TRANSLATIONAL RESEARCH 2009 GRANT PROGRAMS

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  1. TYPE 2 TRANSLATIONAL RESEARCH 2009 GRANT PROGRAMS UW Institute for Clinical and Translational Research (ICTR) Community-Academic Partnership Core (CAP)

  2. UW Institute for Clinical and Translational Research Overall Goal of ICTR Create an environment that facilitates the transformation of research at the University into a continuum extending from investigation through discovery to translation into practice, thereby linking even the most basic research to practical and implemented improvements in human health.

  3. ICTR 2009 Pilot Grant Programs • Clinical and Type1 translational research • maximum $50,000 direct costs, 12 months • Type 2 translational research • maximum $50,000 direct costs, 12 months • NEW: Type 2 translational research community collaboration • maximum $200,000 direct costs, 24 months

  4. The research continuum and role of “type 2” “Realm” of Type 1 “Realm” of Type 2 Basic bench discovery/observation Methods development Pre-clinical animal studies Efficacy Studies Effectiveness research Implementation research Dissemination research Policy research Type 2 translational research solves problems in translating new and existing findings from efficacy studies to improvements in clinical practice and community health; often using a collaborative approach that engages community members, organizations and clinicians as partners in the research process.

  5. How to define “community”? • Community(as defined by NIH for PA-08-077, Community Participation in Research R01) "refers to target populations that may be defined by: geography; race; ethnicity; gender; sexual orientation; disability, illness, or other health condition; or to groups that have a common interest or cause, such as health or service agencies and organizations, health care or public health practitioners or providers, policy makers, or lay public groups with public health concerns.“ • "Community-based organizations“ (as defined by NIH for PA-08-077, Community Participation in Research R01) refer to organizations that may be involved in the research process as members or representatives of the community. Possible community partners include, but are not limited to, Tribal governments and colleges, state or local governments, independent living centers, other educational institutions such as junior colleges, advocacy organizations, health delivery organizations (e.g., clinics, hospitals, and networks), health professional associations, non-governmental organizations, and Federally-qualified health centers."

  6. T2 Pilot Program To support the production of excellent, collaborative research that addresses important health issues for the State of Wisconsin and that will lead to further external, peer-reviewed research projects. T2 Community Collaboration Program To support research partnerships that solve problems in translating clinical and health-related scientific knowledge into meaningful changes in practice, with the goal of improved health outcomes and/or reduced costs in the State of Wisconsin. A community collaboration component is required. Goal of T2 funding programs

  7. Type 2 Grant Priority Areas • Interdisciplinary research teams (across schools/colleges) • New junior-senior investigator partnerships • UW-Madison/Marshfield collaborations • Targeted topic areas: pediatric sciences, health disparities, HIV/AIDS • Novel methodologies • Collaboration with one of the Type 2 research resource programs within ICTR-CAP

  8. Type 2 Grant Logistics T2 Pilot Grants • 12-month project period • Maximum of $50,000 in direct cost support • Single PI per project; multiple co-Investigators • Lead Applicants may submit more than one scientifically distinct proposal • Current Pilot Grant awardees are not eligible to serve as a Lead Applicant • Generation of preliminary data for future grant application T2 Collaboration Grants • 24-month project period • Maximum of $200,000 in direct cost support • Single PI per project; multiple co-Investigators • Lead Applicants may submit more than one scientifically distinct proposal • Research should be beyond pilot phase of investigation • Community collaboration component is required

  9. Lead Applicant (PI) Eligibility • Have applied for membership to ICTR • Be employed by UW-Madison or Marshfield Clinic. • Employment with UW-Madison can mean either sole employment or jointly-appointed faculty • Collaboration with investigators from the UW System or UW Extension is encouraged. • Have the following investigator status: • Assistant professor (tenure track, CHS, or clinical), assistant scientist or K-award recipient • Associate/full professor (tenured, CHS, or clinical) or associate/senior scientist who is proposing to significantly change the direction of his/her research to encompass Type 2 Translational Research activities • Have well-developed plans for using the results of this study to pursue an externally-funded research program.

  10. Type 2 Due Dates • Mandatory Letter of Intent: March 2, 2009 • For those who submitted a LOI for “community collaboration” grant — notification of invitation to submit full proposal: March 11, 2009 • Type 2 Research Workshops: March 16th & 26th, 2009 • Full Applications DUE: May 4, 2009 • Peer Review: May 2009 • ICTR-CAP Steering Committee Review: June 2009 • External Committee Review: June 2009 • ICTR Administrative Review: June 2009 • Award Announcement: July 8, 2009

  11. Evaluation Criteria • Overall scientific excellence • Significance • Innovation • Community collaboration • Type 2 translational nature of research • Likelihood of leading to new peer-reviewed funding • Extent to which the “special criteria” were met

  12. 2008 Type 2 ICTR Awards Examples of 2008 Pilot Research Project Topics • Diabetes (prevention and assessment tools, 2 pediatric and 1 adult) • Remote Assessment of Traumatic Brain Injury • Primary Care Treatment of chronic diseases (chronic kidney disease, depression, colon cancer) • Disease Screening and Process Improvement • Treating tobacco use, drug addiction and medication adherence in partnership with community agencies • Obesity prevention program feasibility studies • Improving management systems in ICU and cardiac care units • Patient-centered and family-centered care assessments

  13. Further questions? See the FAQ document (copies available and on ICTR website) Andrea Dearlove 608.262.7125 adearlove@wisc.edu

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