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VII-2. OUTLINE. Overview of Interim MonitoringEfficacy MonitoringFutility MonitoringAdaptive Designs. VII-3. INTERIM MONITORING. Data and Safety Monitoring Boards (DSMBs) are often given the responsibility of monitoring the accumulating data.The DSMB is responsible for assuring that study participants are not exposed to unnecessary or unreasonable risks.The DSMB is also responsible for assuring that the study is being conducted according to high scientific and ethical standards..

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