Tuberculosis. Dr. Essam El Moghazy NTP Egypt. The Global burden of TB in 2010. 9.4 million new cases in 2009 – 80% in 22 high-burden countries. 1.3 million deaths in 2008 – 98% of these in developing world. 11–13% of incident cases were HIV-positive 380,000 deaths due to TB/HIV.
Dr. Essam El Moghazy
9.4 million new cases in 2009 – 80% in 22 high-burden countries
1.3 million deaths in 2008
– 98% of these in developing world
11–13% of incident cases were HIV-positive
380,000 deaths due to TB/HIV
The diagnosis of adolescents and adults with symptoms suggestive of pulmonary TB should be confirmed by detecting Acid Fast Bacilli (AFB) through the direct smear examination of the sputum.
1. Detection of TB bacilli
Direct smear microscopy
3. Histo-pathological diagnosis of TB
4. Detection of metabolic end products of TB bacilli: BACTEC
5. Detection of DNA of TB bacilli: polymerase chain reaction (PCR)
No chest X-ray pattern is absolutely typical of pulmonary TB
Note. Any person given treatment for tuberculosis should be recorded as a case. Incomplete "trial" tuberculosis treatment should not be given as a method for diagnosis.
patients have received 1 month or more of anti-TB drugs in the past, may have positive or negative bacteriology and may have disease at any anatomical site.
They are further classified by the outcome of their most recent course of treatment
A patient who, while on treatment, remained or became again smear-positive 5 months or later after commencing treatment;
A patient who was initially smear-negative before starting treatment and became smear-positive after the second month of treatment
Re treatment cases