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T. G. A. Histone octomer. C. G C. T A. Histone proteins. G C. C G. T A. A T. A T. C G. 2 nm. G C. T A. Packaging DNA. B DNA Helix. Histone proteins. 2 nm. Packaging DNA. T. G. A. Histone octomer. C. G C. T A. G C. C G. T A. A T. A T. C G. B DNA Helix. G C.

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Presentation Transcript
slide1

T

G

A

Histone

octomer

C

GC

TA

Histone proteins

GC

CG

TA

AT

AT

CG

2 nm

GC

TA

Packaging DNA

B DNA Helix

slide2

Histone proteins

2 nm

Packaging DNA

T

G

A

Histone

octomer

C

GC

TA

GC

CG

TA

AT

AT

CG

B DNA Helix

GC

TA

slide3

11 nm

Histone proteins

Nucleosome

2 nm

Packaging DNA

T

G

A

Histone

octomer

C

GC

TA

GC

CG

TA

AT

AT

CG

B DNA Helix

GC

TA

slide4

GC

CG

TA

AT

AT

CG

GC

TA

Packaging DNA

slide5

GC

CG

TA

AT

AT

CG

GC

TA

Packaging DNA

slide6

11 nm

GC

CG

TA

AT

30 nm

200 nm

AT

CG

GC

TA

Protein scaffold

Packaging DNA

“Beads on a string”

Looped Domains

Tight helical fiber

slide7

11 nm

Nucleosomes

30 nm

700 nm

200 nm

T

Looped Domains

Tight helical fiber

G

C

A

2 nm

Protein scaffold

B DNA Helix

Packaging DNA

Metaphase Chromosome

chromosomes chromatids and centromeres

A packaged chromosome

Chromatid

Identical

chromatid

Replication

Anaphase

Chromosomes, Chromatids and Centromeres

Chromosome arm

Two identical chromosomes

Centromere

Chromosome arm

slide9

Histone proteins

Packaging DNA

T

G

A

Histone

octomer

C

G C

TA

G C

C G

T A

A T

A T

C G

B DNA Helix

G C

T A

slide10

GC

CG

TA

AT

AT

CG

GC

TA

Protein scaffold

“Beads on a string”

Looped Domains

Tight helical fiber

slide11

Nucleosomes

T

Looped Domains

Tight helical fiber

G

C

A

Protein scaffold

B DNA Helix

Metaphase Chromosome