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Translation Blockade at the Ribosomal Binding Site

Learn about the arrest of translation initiation by various modifications at the 30S subunit binding site. Understand how tetracycline, streptomycin, and microcide antibiotics impede peptide transfer. Explore the molecular mechanisms of peptide bond formation.

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Translation Blockade at the Ribosomal Binding Site

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  1. Zablokování vazebného místa

  2. 30S A U G C G C G G A mRNA

  3. A U G C G C G G A 30S

  4. fMET U A C A U G C G C G G A 30S iniciační komplex

  5. fMET U A C A U G C G C G G A 30S iniciační komplex

  6. fMET 50S U A C A U G C G C G G A 30S iniciační komplex

  7. fMet U A C A U G C G C G G A 30S

  8. Arg fMet G C G U A C A U G C G C G G A 30S

  9. fMet Arg P místo A místo U A C G C G A U G C G C G G A 30S

  10. peptidickávazba fMet Arg U A C G C G A U G C G C G G A 30S

  11. fMet Arg U A C G C G A U G C G C G G A 30S

  12. fMet Arg U A C G C G A U G C G C G G A 30S Streptomycin se váže na podjednotku 30S

  13. fMet Arg U A C G C G A U G C G C G G A 30S

  14. fMet Arg G C G A U G C G C G G A

  15. fMet Arg A U G C G C G G A

  16. Gly C C U A U G C G C G G A

  17. Gly C C U A U G C G C G G A

  18. Gly C C U A U G C G C G G A

  19. Blokování translace modifikací podjednotky 30S

  20. fMet U A C A U G C G C G G A 30S tetracyklin

  21. Arg fMet G C G U A C A U G C G C G G A 30S

  22. fMet Arg U A C G C G A U G C G C G G A 30S

  23. Arg fMet G C G U A C A U G C G C G G A 30S

  24. Blokování peptidyltransferázy

  25. 30S A U G C G C G G A mRNA

  26. A U G C G C G G A 30S

  27. fMET U A C A U G C G C G G A 30S iniciační komplex

  28. fMET U A C A U G C G C G G A 30S iniciační komplex

  29. fMET 50S U A C A U G C G C G G A 30S iniciační komplex

  30. fMet U A C A U G C G C G G A 30S

  31. Arg fMet G C G U A C A U G C G C G G A 30S

  32. fMet Arg U A C G C G A U G C G C G G A 30S mikrolidové antibiotikum

  33. fMet Arg U A C G C G A U G C G C G G A 30S

  34. fMet Arg U A C G C G A U G C G C G G A 30S

  35. peptidická vazba se nevytvoří fMet Arg U A C G C G A U G C G C G G A 30S

  36. fMet Arg U A C G C G A U G C G C G G A 30S

  37. Blok přenosu peptidyl tRNA z místa A do P

  38. 30S A U G C G C G G A mRNA

  39. A U G C G C G G A 30S

  40. fMET U A C A U G C G C G G A 30S iniciační komplex

  41. fMET U A C A U G C G C G G A 30S iniciační komplex

  42. fMET 50S U A C A U G C G C G G A 30S iniciační komplex

  43. fMet U A C A U G C G C G G A 30S

  44. Arg fMet G C G U A C A U G C G C G G A 30S

  45. fMet Arg P místo A místo U A C G C G A U G C G C G G A 30S

  46. peptidickávazba fMet Arg U A C G C G A U G C G C G G A 30S

  47. fMet Arg U A C G C G A U G C G C G G A 30S Streptomycin se váže na podjednotku 30S

  48. fMet Arg U A C G C G A U G C G C G G A 30S

  49. fMet Arg U A C G C G A U G C G C G G A 30S

  50. fMet Arg A U G C G C G G A 30S

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