1 / 13

ايمني شناسي Immunology : The Immune System in Health & Disease

ايمني شناسي Immunology : The Immune System in Health & Disease. دوره كارشناسي علوم آزمايشگاهي. منابع. Immunobiology : The Immune System in Health & Disease Sixth Edition Charles A. Janeway, Paul Travers, Mark Walport, Mark Shlomchik. Immunlogy Sixth Edition Kuby, Kindt, Goldsby, Osborn.

norris
Download Presentation

ايمني شناسي Immunology : The Immune System in Health & Disease

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. ايمني شناسي Immunology: The Immune System in Health & Disease دوره كارشناسي علوم آزمايشگاهي

  2. منابع Immunobiology: The Immune System in Health & DiseaseSixth EditionCharles A. Janeway, Paul Travers, Mark Walport, Mark Shlomchik ImmunlogySixth EditionKuby, Kindt, Goldsby, Osborn

  3. Figure 1-1 Edward Jenner 1796 diccovered that Cowpox or vaccinia induced protection against human smallpox

  4. ايمونولوژيImmunology • اهميت ايميونولوژيImportance of Immunology • ايمني چيست؟What is Immunity? • اجزاء سيستم ايمنيComponents of Immune System • عملكرد سيستم ايمنيFunction of Immune System

  5. اهميت ايميونولوژيImportance of Immunology • Host Defence : Host Defence The body is under constant attack by pathigenic microorganisms in the environment. • Obviously protecting the host from infection is the main job for the immune system • Pathogen : an infectious agent that causes disease Infection or disease occurs when a microorganism (pathogen) manages to overcome host defenses to make a local site of infection and multiplication. • Pathogen: There are four broad categories of disease-causing microorganisms or pathogens; Viruses, Bacteria, Pathogenic Fungi, other complex eukaryotic organisms termed Parasites

  6. ايمني چيست؟What is Immunity? • Immunity (derived from immunitas: Latin for exemption from prosecution) • Immunity means protection from disease and especially infectious disease. • Resistance to particular pathogens or to their toxins or metabolic by-products • Then, antigens elicit immune responses

  7. اساس كار سيستم ايمنيBase of Immune System Function • Based on the ability to distinguish “self” from “non-self” antigens • If not, immune responses are elicited to their own tissues as they are foreign agents. • Most individuals do not suffer from autoimmune disease because they have developed tolerance towards their own (self) tissues. • The immune response can cause the autoimmune diseases common to man such as diabetes, rheumatoid arthritis

  8. اجزاء سيستم ايمنيComponents of Immune System • بافتها و اعضاء سيستم لنفاوي Lymphoid Organs • سلولهاي لنفاوي Lymphoid Cells

  9. بافتها و اعضاء سيستم لنفاويLymphoid Organs 1 • Primary (Central) Lymphoid Organs • (Lymphocytes are generated) • Bone Marrow • Thymus

  10. بافتها و اعضاء سيستم لنفاويLymphoid Organs 2 • Secondary (Peripheral) Lymphoid Organs • Lymphocytes are maintained, Adaptive Immune Responses are initiated • Lymphatic Vessels & Capillaries • Lymph nodes • Spleen • Lymphoid tissues associated with mucosa • Gut associated Tonsils, • Peyers Patches • Appendix • Lymphoid Follicles (Bronchial-Associated Lymphoid Tissue (BALT), Mucosal-Associated Lymphoid Tissue (MALT)

  11. Primary (Central) Lymphoid Organs • مغز استخوان Bone Marrow • در سنين پايين در همه استخوانها • در سنين بالا در استخوانهاي دراز از بين مي رود • محل بلوغ لنفوسيتهاي B است • تيموس Thymus • در سنين پايين فعال است و در سن بالا تحليل مي رود • محل بلوغ لنفوسيتهاي T است

  12. Thymus • small in an adult • site of T lymphocyte production • secretes thymosins 16-14

  13. Figure 1-7

More Related