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Natural Sciences and Social Responsibilities of Leading Universities: Pacific Case Vladimir I. Kurilov, S.J.D., LL.D. President, Far Eastern National University APRU APM Open Forum, 29 June 2009 We all are united by global challenges and global problems… The economic crisis Pandemics
Natural Sciences and Social Responsibilities of Leading Universities: Pacific Case
Vladimir I. Kurilov, S.J.D., LL.D.President, Far Eastern National UniversityAPRU APM Open Forum, 29 June 2009
today we have:
but are we really ready to produce adequate global answers?
The Russian philosopher Alexander Gerzen called the Pacific Ocean "the Mediterranean of the future humankind“ (1858). However, the integration of Pacific society is still far behind the integration of European and other Mediterranean countries; political and economic structures like the EU will be impossible in the Pacific Rim for many decades. Pacific universities are responsible for creating integrated regional economic, cultural, educational and research societies of the future. APRU should be a flagship of these activities.
on the global level.
a powerful catalyst for these activities.
FENU can host and coordinate this activity
in its World Ocean Innovative Technological Center.
Why we are able and interested to do this?
Comanche, FENU’s deepwater (up to 6 km) robot: environmental and mineral resources research – produced by SUB-ATLANTIC Co., Great BritainWorld Ocean Innovative Technological Center: Comprehensive Multidisciplinary Approach
to World Ocean as a whole and its various specific regions: complex systematic approach to complex phenomena
for underwater mineral resources, detailed underwater mapping of various parameters, forecasts of dangerous and catastrophic events
and processes, navigation safety research, monitoring of biological resources, production
of medicines and biologically active compounds;
and hydro-meteorological research development of marine research technologies
Recent FENU Research Results in Marine Biology and Biotechnology
FENU tries to answer global challenges with research
at the cutting edge of technology; we want to share the most interesting and important results of this research obtained by one subdivision of the FENU World Ocean Innovative Technological Center – the Academy
of Ecology, Marine Biology and Biotechnology…
New type of vaccines composed of natural marine substances: lipids and saponins
Department of Biochemistry and Biotechnology
Purpose of the research:fundamental research in the field of immunology and vaccinology to produce more effective immunological adjuvants and new types of nontoxic immune-stimulating complexes(ISCOM’s).
Results:A new carrier of subunit protein antigens was developed that demonstrates more potential immunological properties than commonISCOM’sand Freund’s adjuvant; this carrier was named TI-complex. Immunological research shows high safety and great immunomodulating potentialof TI-complexes and their components.TI-complexes are able to enhance significantly theimmune response against bacterial antigens. This development combines the increasing efficacy andsafety of antigen preparations.
ISCOM-based vaccines form a new type of vaccines. Conventional ISCOMs include artificialnanoparticles, composed of saponinQuil A, cholesterol and phospholipids(usually from egg yolk). These particles have size about 40 nm, a typical size of virions. ISCOM is an effective media for presentation of antigens to immunosites; it is also a potent adjuvant.
Department of Biochemistry and Biotechnology has developed immune-stimulating nanocarriers of subunit antigens that have super-molecular structure of a new type. These carriers are composed of well-investigated biologically active compounds derived from marine hydrobionts. Components of these carriers are highly safe for humans and have greater biological properties in comparison to well-known analogs. Application of these carriers in the field of development of new subunit vaccines promises significant cost reduction.
In 2008, three patents have been issued for these research results:
Patent No. 2319506(application No. 2005131645/13(035476)) Patent holder: Far Eastern National University
Authors: N.M. Sanina, A.M. Popov, I.A. Li, E.Ya. Kostetskiy, A.B. Tsybulsky, and V.L. Shnyrov
Patent No.2322259( application No. 2006123270/13(025252)) Patent holder: Far Eastern National University
Authors: A.M. Popov, I.A. Li, E.Ya. Kostetskiy, N.M. Sanina, A.B. Tsybulsky, V.L. Shnyrov, and A.N. Mazeika
Patent No.2311926 (application No. 2006104795\13(005189))
Patent holder: Far Eastern National UniversityAuthors: E.Ya. Kostetskiy,A.M. Popov, N.M. Sanina I.A. Li, A.B. Tsybulsky, and V.L. Shnyrov
Electron photomicrography of conventional ISCOM-matrices (Kersten, Crommelin, 1995)
Powerful immune-stimulating nanocarriers have been produced from Pacific marine hydrobionts; these results will be used in medical applications.
Electron photomicrography of TI-complexes
Lipids of marine invertebrates are used as potential cryoprotectors
Purpose of the research:screening of new medicines with potential cryoprotector properties and optimization of their concentration in cryoprotective mixtures that provide maximum cell viability of marine hydrobionts after cryopreservation.
The findings provide the basis for creation of new cryoprotectors for cells of marine hydrobionts. It is an essential step to creation of an animal cryobank.
In 2008, a patent was issued for these research results:
Patent No. 2314687(applicationNo. 2005131645/13(035476)) Patent holders: Far Eastern National University and Institute of Marine Biology, Far Eastern Branch of the Russian Academy of SciencesAuthors: N.A. Odintsova, A.V. Boroda, N.V. Ageenko, and E. Ya. Kostetskiy
Impressive results were obtained in the field
of marine hydrobiont cryopreservation. These results will help to protect and study
the biological diversity of the Ocean; they are important for survival of many marine species.
Purpose of the research: development of the biopolymer matrixes which program chemical and mechanical induction of stem cell differentiation to produce artificial tissue implants
FENU researchers develop unique biopolymer matrixes obtained from marine invertebrates; these matrixes will be used for stem cell production of artificial tissue implants.
Stem cell applications in medicine will give people of the current and future generations many additional decades of high quality life; marine biota will help these technologies
to become more safe and effective through nano-sized processes.
to the solid or gel warp
to the polymer film
Putting the stem cell suspension on the matrix
Using the constructed tissue implant
Induced stem cells
Proteins of fibrillar matrix
Proteins – differentiation inducers (1sttype)
Proteins – differentiation inducers (2ndtype)
Glycoproteinsconnecting matrix fibrilles
Amorphous matrix consisting of glycopolymer and mineral substances
Micropatterned nanoheterogeneous matrixes may direct stem cells to multiple pathways:
Stem cell active proliferation
Growth retardation with pluripotency preservation
One of the matrix types
Directed growth and differentiation along the composite tracks
Neuron formation for further tissue implants
Purpose of the research: identifying trends and reasons of changes of coastal ecosystem biodiversity in the Sea of Japan and developing methods to identify their taxonomic composition and relationships
The structure and hierarchy of temporal populations of Pacific salmon (genus Oncorhynchus) was researched.
The species composition of the following families in the north-west part of the Sea of Japan was studied: Stichaeidae, Pleuronectidae, Syngnathidae.
Molecular phylogenetic study of cyprinoid fish and flatfish in the waters of the Russian Far East was performed.
The structure of coastal ecosystems was studied along with composition of autumn zooplankton of the North-West part of the Sea of Japan in the shallow bay Vytyaz’ (within Peter the Great Bay) and Kievka (northern part of Primorsky region).
Intensive FENU research is focused on the protection of marine ecosystem biodiversity.
Purpose of the research: protection of seashore plant communities of the Russian Far East and adjacent countries
Monitoring studies of flora were performed at previous test areas along the pipeline of the Sakhalin-2 project.
New test areas were established at aquatic and swamp regions; conditions of rare and endangered species of plants were measured.
The Department of Botany continues its collaboration with the National University of Chonbuk (Korean Republic), conducting their joint research of moss. Collection of 1,000 floral specimens from Eastern Asia were identified, handling of specimens of the family Ericaceae and identification of herbarium was performed for the monograph dedicated to Korean flora. More than 800 herbarium speciments were identified.
Simultaneous solution of economic and ecological problems, a typical task of our time, was used for the famous Sakhalin-2 oil & gas extraction project; FENU researchers were responsible for the ecological component
of this project.
The research identified technological parameters of nano-size multi-layer films that allow to reduce the size of magnet domains by 5 times in relation to one-layer films to 430 nm. Patent application has been submitted for these research results.
Ultra-thin multi-layer iron/semiconductor nanogeterostructures were produced requiring 10 times less magnet field level for magnetic reversal in relation to one-layer films.
Magnetic nano-points sized about 100 nm were studied for developing ultra-dense data recording media.
We pay a special attention to development of research in nano-technologies; it is a real solution to mineral resource depletion problem. FENU’s research team in this field, one of the leading in Russia, is specialized in multi-layer films of nano-level.
Russian Island Campus, Stage 1 (2008 - 2012)
Conference Center(85,000 m2): Institute of Oriental Studies, Institute of Russian Language and Culture, Institute of Foreign Languages, Institute of History, Philosophy and Culture (up to 4,200 students)
Press Center (40,000 m2): Institute of Mass Communications, Far Eastern Institute of Innovative Technologies and Quality, Institute of Mathematics and Computer Science (up to 3,300 students)
Dormatories and Apartments (295,000 m2): Dorms for 9,000 students and apartments for 1,000 faculty members, researchers and staff
In total, the stage 1 campus infrastructure will support face-to-face higher education for 12,000 students, including up to 1,000 international students
Degree programs in 34 specialties will be provided on this campus
The opportunities of FENU participation in APRU research and education activities, including World Ocean studies, will be considerably increased in the near future. In 2009, FENU will become the 3rd federal university
of Russia; by 2012 FENU will build the best modern university campus of Russia, capable to host 6,000 participants of APEC 2012 Summit. The construction of this campus started in April 2009. But much more important than the campus construction, is the federal program of all-dimensional FENU development, including purchase of unique research equipment. The first federal funds transfer for this purpose was received by FENU in May 2009.
Russian Island Campus, Stage 2 (2012 - 2025)
FENU Russian Island Campus extension has been planned in detail up to 2025…
Campus Zone A (Northern Campus Zone)
Institute of Physical Education and Sports
(500 students, 5,000 m2)
International Business School, Schools of Finance and Economics (9000 students, 35,100 m2)
Law School (4,000 students, 23,600 m2)
Institute of Research Information – Fundamental Library (20,000 m2)
Dorms for 13,000 students
In total, the Northern Campus Zone infrastructure will support face-to-face higher education for 13,500 students
Academic buildings: 88,700 m2 or more
Campus Zone B (Central Campus Zone)
Institute of Pedagogy and Education
(2,200 students, 10,400 m2)
Institute of Psychology and Social Science
(2,000 students, 9,500 m2)
Institute of Professional Development and Institute of Doctoral and Post-Doctoral Programs (7,000 m2)
Institute of Pre-University Training, Lyceum (University-based high school) (4,000 students, 25,000 m2)
Dorms for 6,000 students
In total, the Central Campus Zone infrastructure will support face-to-face education for 8,200 students
Academic buildings: 51,900 m2 or more
Russian Island Campus, Stage 2, Zones C & D (2012 - 2025)
Campus Zone C (Ajax Campus Zone)
Institute of International Tourism and Hospitality
(3,000 students, 16,500 m2)
Vladivostok Institute of International Relations in the Pacific Rim (3,800 students, 21,000 m2)
Institute of Art and Culture (1,000 students, 8,900 m2)
Center of Public Political Technologies in the Pacific Rim and Asian Studies (2,300 m2)
Pacific Center of Russian Language and Culture (2,000 m2)
Center of International Education (2,000 students, 8,000 m2)
Dorms for 7,500 students
In total, the Ajax Campus Zone infrastructure will support face-to-face higher education for 9,800 students, including 3,000 international students
Academic buildings: 58,700 m2 or more
Campus Zone D (Southern Campus Zone)
Mathematical and Natural Sciences schools (2,000 students, 40,000 m2)
Medical School (4,000 students, 33,600 m2)
Technical and Technological schools
(6,000 students, 43,200 m2)
Innovative Technological Center in Marine Sciences
Innovative Technological Center of NanotechnologiesandNano-Engineering (11,800 m2)
Biotechnology R&D Park (5,400 m2)
Business Incubator (4,000 m2)
Center of Technical Support (5,000 m2)
Dorms for 11, 400 students
2,200 engineers and researchers will be employed
in the Southern Campus Zone research centers
In total, the Southern Campus Zone infrastructure will support face-to-face higher education for 12,000 students
Academic buildings: 164,800 m2 or more
Russian Island Campus, Stage 2 (2012 - 2025)
Infrastructure for General Purposes:
Main Administrative Building (10,000 m2)
Apartments for faculty members, researchers and staff (840,000 m2)
Kindergartens for 5,590 pupils
General secondary schools for 12,040 students
Specialized secondary schools
for 1,290 students
Clinics for 2,580 visitors per shift
Open air sports facilities
In our new campus, we want to build a model of a sustainable, educated, high tech, interactive society of the future. Its location on a wild Pacific island near a city downtown, near the major Pacific sea gate of Russia is symbolic. We want to develop advanced, internationally integrated economy, at the same time protecting and studying the wild nature; we focus on the Pacific Ocean as an extending environment of the future humankind. Here, in the Pacific Rim, all of us university people must unite and interact in answer to global economic and ecological problems that we face and foresee.
The Place for APRU World Ocean Institute in the Structure of Other APRU Activities
+ APRU World Ocean Institute (AWOI) - FENU’s and Russian Academy of Sciences’ proposal)
Human Capital Development Activities:
+ World Ocean Symposiums as annual events organized by AWOI
AWOI Standing Committee:
AWOI may be formed as a consortium of APRU member university subdivisions (schools, research centers, laboratories), related to oceanic studies, such as the FENU World Ocean Innovative Technological Center
Annual APRU World Ocean Symposium:
Research and Educational Projects
The first APRU World Ocean Symposium can be hosted by FENU and the Far Eastern Branch of the Russian Academy of Sciences in Summer 2010 or 2011
Website of the Far Eastern National University:http://fenu.ru
FENU President’s email: firstname.lastname@example.org
FENU International Dept. email:email@example.com