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Searching EMBASE Janet West Principal Pharmacist Medicines Information Southern General Hospital NHS Greater Glasgow &am PowerPoint Presentation
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Searching EMBASE Janet West Principal Pharmacist Medicines Information Southern General Hospital NHS Greater Glasgow & Clyde. What is EMBASE?. What is EMBASE?. Major biomedical & pharmaceutical database European focus Subject coverage focuses on human medicine

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Presentation Transcript
slide1
Searching EMBASE

Janet West

Principal Pharmacist Medicines Information

Southern General Hospital

NHS Greater Glasgow & Clyde

what is embase
What is EMBASE?

What is EMBASE?

  • Major biomedical & pharmaceutical database
  • European focus
  • Subject coverage focuses on human medicine
    • also includes related disciplines e.g health economics, hospital management
background
Background

Background

  • >11 million records
  • 1974 onwards
  • >5000 journals
  • >70 countries
  • ~580,000 records added annually
  • ~80% records have author written abstract
embase medline
EMBASE <> Medline

Medline vs EMBASE

  • EMBASE indexes more drug related literature
  • EMBASE covers more European & Far Eastern journals
  • Medline covers more US journals
  • EMBASE is updated faster – average = 10 - 15 working days for full article to appear c.f. 6-8 weeks for Medline (30% within 30 days , 60% within 60 days)
  • Overlap between Medline & Embase = ~30% therefore always search both
searching embase
Searching EMBASE
  • Controlled vocabulary = EMTREE
  • Uses natural language e.g. chronic fatigue syndrome [EMBASE] v fatigue syndrome, chronic [Medline]
  • US spellings rather than British e.g. estrogen rather than oestrogen
  • INNs used where possible
  • Acronyms & abbreviations mostly avoided
slide7

EMTREE

  • Hierarchical tree consisting of:
  • EMTREE is divided into 15 facets (A  Q)
  • Largest = facet C & facet D
  • C = physical diseases, disorders and abnormalities
  • D = chemicals and drugs (21,000 terms)
searching embase8
Searching EMBASE
  • ‘Explode’ and ‘major’
  • ~20 descriptive terms applied to each record (sometimes many more)
  • 3 – 5 are given importance (major)
searching embase9
Searching EMBASE
  • Dialog NHS interface:
    • Type in words and map to thesaurus

or

    • Use browse function

or

    • Enter the term

EMBASE

using subheadings
Using subheadings
  • Many more subheading options for drugs compared with Medline

e.g. diclofenac

EMBASE

check date term was added
Check date term was added
  • Must check when a term was added (in scope note – yellow post-it note)
  • May need to search free text as well to pick up articles before the entry date of that term with these words in

e.g. grapefruit juice

NB - CARE as may not be

a topic of the article

free text
Free Text
  • Free text searches also useful when:-
    • there is no appropriate match in the EMTREE thesaurus for your term,
    • the concept is very new to the literature, or
    • the concept has a very specific name, such as ‘Waterlow Score’
trade name searching
Trade name searching
  • Drug / device trade names can be searched
  • Articles are indexed with trade names when relevant
  • Useful when searching for comparative info

e.g. Slophyllin, Uniphyllin

cas number searching
CAS number searching
  • No real need to do this in EMBASE
  • However it is still possible to do – see drop down menu
  • All medicines have EMTREE terms – even recently licensed ones (as far as I can tell!) e.g. duloxetine, rasagiline etc
embase limits
EMBASE limits
  • Limit searches in similar way to Medline
  • Two ways of limiting
  • Less publication type limit options (but see next slide), less age limit options
publication types
Publication types
  • Publication types have their own facet / tree top of EMTREE terms that are searchable
  • Facet J: types of article or study
  • Build up your search and combine in the usual way (using BOOLEAN) with other search terms
worked example 1
Worked example 1
  • Are there any papers about SSRIs or SNRIs being used in the treatment of Huntington disease?
worked example 2
Worked example 2
  • Are there any articles which discuss using high dose vitamin supplementation to treat autistic disorders ?

EMBASE