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RACING MEDICATION AND TESTING CONSORTIUM

protect the interests of the racing public. RMTC was formed in 2002 as a 501 (c)(3) ... The Jockey Club & Kentucky Horse Racing Authority. Tax-deductible ...

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RACING MEDICATION AND TESTING CONSORTIUM

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    Slide 1:RACING MEDICATION AND TESTING CONSORTIUM Dan Fick The Jockey Club Executive Director & Executive Vice President

    Slide 2:Topics Mission Uniform Model Rules Research Anabolic Steroids Drug Testing Funding

    Slide 3:Mission of RMTC To develop, promote and coordinate, at the national level, policies, research and educational programs that seek to: ensure fairness and integrity of racing ensure the health and welfare of racehorses and participants protect the interests of the racing public RMTC was formed in 2002 as a 501 (c)(3) charitable organization; donations are tax deductible.

    Slide 4:AAEP AQHA Arabian Jockey Club Breeders’ Cup California TB Trainers Churchill Downs Del Mar Hambletonian Society Harness Tracks of America Jockey Club      Jockeys’ Guild Keeneland Kentucky TB Association Magna Entertainment National HBPA NTRA NYRA Oak Tree RCI THA TOBA TB Owners of California TRA TRPB USTA

    Slide 5:RMTC Officers Executive Director: Dr. Scot Waterman Chairman: Dr. Bobby Lewis - AAEP Vice Chairman: Chris Scherf - TRA Vice Chairman: Alan Foreman - THA Secretary: Dr. Rick Arthur - CHRB Treasurer: Tom Charters - Hambletonian CEO: Dan Fick - The Jockey Club

    Slide 6:RMTC Model of Operation Goals: Uniform regulation Level playing field Welfare and safety of participants Implementation Strategy: Review existing research New research Scientific Advisory Committee Consensus of directors

    Slide 7:Model Rules Phase 1 (2005) Veterinary Practices Prohibited Practices Drug Classifications/Categorization Permitted Therapeutics: Race Day Voluntary use of Lasix Adjuncts permitted pending research Anti-ulcer medications One of three NSAID – Bute, Banamine & Ketoprofen – 24 hours

    Slide 9:Uniform Penalties (2006) Three-tiered grid system simplified existing RCI penalties Significantly increases penalties for illegal and prohibited performance-enhancing drugs Reduces penalties for therapeutic medication mistakes Redefines trainer responsibility Mitigating and aggravating circumstances “checklist” for stewards Added penalties for other culpable licensees: veterinarians, owners and grooms Adopted as rule or policy in 25 states

    Slide 10:Uniform Model Penalties Policy Class A – Illegal, not approved, significant performance enhancement Lifetime: 1st Offense – Minimum 1 year & $ 10,000 Maximum 3 year & $ 25,000 3rd Offense – Minimum 5 year & $ 50,000 Maximum 10 year & $100,000 Class C – Therapeutic medications at less than performance enhancing levels 365 Days 1st Offense – Minimum $ 500 2nd Offense – Minimum 15 day & $ 1,000 3rd Offense – Minimum 30 day & $ 2,500

    Slide 11:Regulation of anabolic steroids Limited to four FDA-permitted anabolics Stanozolol (Winstrol) Boldenone (Equipoise) Nandrolone Testosterone 30-45 days withdrawal time Out-of-competition testing Blood-doping agents – EPO & Darbypoietin Illegal & prohibited drugs

    Slide 12:Research Research grants - $965,000 to date Performance enhancers Erythropoietin, Ethanol and Cone Snail Venom Therapeutics Procaine Penicillin, Flunixin, Clenbuterol and Amicar Environmental contaminants Morphine and Cocaine Research on 50 therapeutics and anabolic steroids Unknowns from backstretch contacts 25-horse research training stable Dr. Don Catlin – Anti-Doping Research Lab AS I HOPE YOU KNOW, CALIFORNIA HAS A SIGNIFICANT PRESENCE ON THE RMTC BOARD WITH DR. RICK ARTHUR, DICK MANDELLA, CRAIG FRAVEL, ED HALPREN & DREW COUTO. YOU SHOULD ALSO KNOW THAT THE RMTC IS NOW HEADQUARTERS OUT OF THE JOCKEY CLUB’S LEXINGTON OFFICE. CURRENTLY, OUR PRIMARY FOCUS IS ESTABLISHING WITHDRAWAL GUIDELINES FOR THERAPEUTIC MEDICATIONS. IN CONCERT WITH THIS EFFORT, WE HAVE CALLED FOR STRICT REGULATION OF ANABOLIC STEROIDS IN RACEHORSES. WE ARE ALSO IN THE FINAL STAGE OF AN AGREEMENT WITH THE KENTUCKY HORSE RACING AUTHORITY TO FUND A 25-HORSE RESEARCH STABLE TO DEVELOP THESE WITHDRAWAL GUIDELINES. WORKING IN CLOSE COOPERATION WITH THE TRPB, WE ARE DRAFTING A TRACK SECURITY GUIDEBOOK AND WILL CONTINUE TO PROVIDE ASSISTANCE WITH BACKSTRETCH SECURITY AT MAJOR RACING EVENTS. WE NOW HAVE 33 STATES THAT HAVE ADOPTED OUR RECOMMENDED THERAPEUTIC MEDICATION RULES, AND MANY STATES, INCLUDING CALIFORNIA HAVE ADOPTED OUR RECOMMENDED PENALTY GUIDELINES. FINALLY, WE ARE WORKING WITH THE RCI DTSP COMMITTEE ON QUALITY ASSURANCE FOR TESTING LABORATORIES. ??????????????????????AS I HOPE YOU KNOW, CALIFORNIA HAS A SIGNIFICANT PRESENCE ON THE RMTC BOARD WITH DR. RICK ARTHUR, DICK MANDELLA, CRAIG FRAVEL, ED HALPREN & DREW COUTO. YOU SHOULD ALSO KNOW THAT THE RMTC IS NOW HEADQUARTERS OUT OF THE JOCKEY CLUB’S LEXINGTON OFFICE. CURRENTLY, OUR PRIMARY FOCUS IS ESTABLISHING WITHDRAWAL GUIDELINES FOR THERAPEUTIC MEDICATIONS. IN CONCERT WITH THIS EFFORT, WE HAVE CALLED FOR STRICT REGULATION OF ANABOLIC STEROIDS IN RACEHORSES. WE ARE ALSO IN THE FINAL STAGE OF AN AGREEMENT WITH THE KENTUCKY HORSE RACING AUTHORITY TO FUND A 25-HORSE RESEARCH STABLE TO DEVELOP THESE WITHDRAWAL GUIDELINES. WORKING IN CLOSE COOPERATION WITH THE TRPB, WE ARE DRAFTING A TRACK SECURITY GUIDEBOOK AND WILL CONTINUE TO PROVIDE ASSISTANCE WITH BACKSTRETCH SECURITY AT MAJOR RACING EVENTS. WE NOW HAVE 33 STATES THAT HAVE ADOPTED OUR RECOMMENDED THERAPEUTIC MEDICATION RULES, AND MANY STATES, INCLUDING CALIFORNIA HAVE ADOPTED OUR RECOMMENDED PENALTY GUIDELINES. FINALLY, WE ARE WORKING WITH THE RCI DTSP COMMITTEE ON QUALITY ASSURANCE FOR TESTING LABORATORIES. ??????????????????????

    Slide 13:RMTC Research Program RMTC is also focused on developing tests for “designer” drugs “Unknown” acquisition and analysis: RMTC works with sources and purchases products being marketed as “performance enhancing” Over a dozen vials and syringes have been analyzed over the past two years Majority contain “voodoo” products and are of little concern In 2007, one unknown led to a federal investigation and prosecution of a “race-day medication” website

    Slide 15:Withdrawal Times Research Identified drugs with legitimate uses Prioritized drugs into five groups Collected previous science on each drug If science is insufficient then perform administrations on a minimum of 20 horses Research costs of administration, collection and analysis are $20,000 up to $40,000 depending on drug Plasma is preferred but some drugs will have both urine and plasma collected Ultimate goal: uniform withdrawal time with a corresponding threshold level of drug which regulates the withdrawal time

    Slide 16:Withdrawal Times Research Priority Group 1 Acepromazine Butorphanol Detomidine Glycopyrrolate Lidocaine Mepivacaine Methocarbamol Pyrilamine Priority Group 2 Boldenone Dantrolene Dexamethasone Fluphenazine Hydroxyzine Nandrolone Stanozolol Testosterone

    Slide 17:Withdrawal Times Research Priority Group 3 Albuterol Betamethasone Diclofenac Methylprednisolone Reserpine Triamcinolone Trichlormethiazide Xylazine Priority Group 4 Atropine Beclomethasone Buscopan Cromolyn Isoxsuprine Pentoxyfylline Phenytoin Prednisolone

    Slide 18:Withdrawal Times Research Priority Group 5 Diazepam Dipyrone Fluorprednisolone Guaifenesin Isoflupredone Prednisone Research finished Aminocaproic Acid Carbazochrome Clenbuterol Procaine Penicillin Cimetidine DMSO Flunixin Furosemide Ketoprofen Omeprazole Phenylbutazone Ranitidine

    Slide 19:Withdrawal Time Database Withdrawal times posted for 18 jurisdictions and over 70 drugs Database is searchable by drug and by jurisdiction Over 2,000 unique users in first month of availability Help us add more (New Mexico) www.rmtcnet.com, click on “Withdrawal Times” tab at top of page

    Slide 25:Anabolic steroids Why now? Several surveys showed extremely high levels of use Perception and level of public consciousness of anabolic steroids Federal scrutiny of major league sports Legislation to ban steroids introduced in Congress Harmonizes the U.S. internationally

    Slide 26:Anabolic steroids Model rule approved by RCI in April 2007 Revised by RCI in December 2007 to cover the intact male Model rule contains urinary thresholds for 4 anabolic steroids that are permitted by FDA Plasma thresholds will be added once administration studies are completed this fall

    Slide 27:Anabolic Steroids AR, AZ, CO, DE, IA, IL, IN, PA, VA, WA have adopted this model rule At least 12 other states have started the adoption process RMTC & RCI have encouraged every state to be done with the adoption process by 12/31 Recommendations for implementation approved by RMTC & RCI in March 2008

    Slide 28:Anabolic Steroids RMTC Board recommends: 90-day grace period on penalty enforcement when rule is introduced Notification to owner/trainer for overage, No fine or loss of purse absent aggravating circumstances After 90 days, jurisdictions should follow the penalty guidelines in the model rules $500 and loss of purse for 1st violation Pre-entry testing must be made available in some form

    Slide 29:Anabolic Steroids RMTC Board recommends: Boldenone, stanozolol, nandrolone and testosterone should not be administered within 30 days of a race If needed outside of 30 days, must be documented by veterinarian, must include diagnosis and filed with the regulatory body Horse should then test negative before being allowed to enter. Claimed horses may be tested on request and at the cost of the claimant. If positive, claim can be voided and cost of testing borne by original owner.

    Slide 30:Anabolic Steroids Significant interest at the federal level on this issue Reps from RMTC, RCI, NTRA met with congressional staffers in Jan ‘08 Alex Waldrop recently testified in front of House Energy and Commerce Sub-committee Interstate Horseracing Act is in play, state regulation of drug control also in jeopardy Congressmen Whitfield & Rush drafting legislation with possible hearing in mid-June.

    Slide 31:Drug Testing Objectives Uniform Testing Standards for chain of custody, split and frozen samples Standard operating procedures and testing protocols Quality assurance and blind sampling Laboratory accreditation Future Considerations National industry-owned reference laboratory Potential for consolidation of 18 existing drug-testing laboratories

    Slide 32:Funding $2.7 million bridge financing from industry organizations 2003-2006 2007 Contributions = $683,126 2008 Projected Funding: $1 per start from horsemen and racetracks $700,000 from industry organizations $500,000 research and testing grants fromThe Jockey Club & Kentucky Horse Racing Authority Tax-deductible donations from individuals

    Slide 33:RMTC: Contact Us www.rmtcnet.com

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