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Comprehensive Management of Advanced Ovarian Carcinoma Symptoms in Mrs. S: A Case Study

This case study explores the clinical presentation and management of Mrs. S, a 59-year-old with advanced ovarian carcinoma. Following the exhaustion of chemotherapy options and the inability for surgical intervention due to intra-abdominal disease and metastases to the liver and bones, Mrs. S experiences a range of debilitating symptoms, including nausea, bloating, back pain, and bowel obstruction. This analysis covers potential causes of her symptoms, necessary investigations, treatment options, and the management of her worsening condition, emphasizing palliative care principles in advanced cancer.

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Comprehensive Management of Advanced Ovarian Carcinoma Symptoms in Mrs. S: A Case Study

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  1. Case Study May 2009

  2. Mrs S age 59 with carcinoma of ovary • Intra abdominal disease • Surgery no longer an option • Chemotherapy options exhausted • Metastases in liver and bones

  3. Mrs S develops nausea and bloating after a small meal • What might be the cause? • What would you do?

  4. Mrs S now develops back pain at level of L3 • What investigations might you need? • What treatment(s) might you consider? • What other medication(s) might you also need to prescribe?

  5. She now develops sciatic nerve root pain in addition • What might you need to exclude? • What additional analgesia might you consider?

  6. Mrs S now develops abdominal distension, pain (not colic) ,vomiting and some constipation • What might the diagnosis be? • What would be your initial management of symptoms include?

  7. She now develops a complete bowel obstruction with colic • How might you change your management? • What route would you use for medications?

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