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Hard gelatin and vegetarian capsules are pivotal in the pharmaceutical and nutraceutical industries, serving as primary vehicles for delivering medications and supplements
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Sahasra Yogam: Pioneering Authentic Ayurveda and Holistic Wellness Hard gelatin and vegetarian capsules are pivotal in the pharmaceutical and nutraceutical industries, serving as primary vehicles for delivering medications and supplements. Sahasra Yogam, based in Hyderabad, India, has established itself as a notable manufacturer in this domain, offering comprehensive services in hard gelatin and vegetarian capsule production. Understanding Hard Gelatin and Vegetarian Capsules Hard gelatin capsules, often referred to as hard-shell or two-piece capsules, are solid dosage forms designed to encase medicinal agents or inert materials within a small shell. These capsules consist of two cylindrical sections—a cap and a body—each with one rounded, closed end and one open end. The body, having a slightly smaller diameter, fits snugly into the cap. Traditionally, these shells are fabricated from gelatin, a purified protein derived from animal collagen. However, with the rise in vegetarianism and veganism, as well as cultural and dietary restrictions, there has been a significant shift towards vegetarian capsules. These are typically made from plant-derived materials like hydroxypropyl methylcellulose (HPMC), offering an alternative to animal-based gelatin. Manufacturing Process of Hard Gelatin Capsules The production of hard gelatin capsules involves several meticulous steps to ensure quality and uniformity: 1.Preparation of Gelatin Solution: Gelatin is dissolved in demineralized water heated to about 60–70°C, creating a concentrated solution containing 30–40% w/w gelatin. This viscous solution may also include colorants and processing aids to achieve the desired capsule characteristics. 2.Dip-Coating: Pairs of standardized steel pins, arranged in rows on metal bars, are dipped into the gelatin solution maintained at approximately 50°C. The viscosity of the gelatin solution is a critical parameter as it affects the downstream manufacturing process and plays a major role in capsule shell wall thickness. 3.Rotation and Drying: After dipping, the pins are rotated to ensure even distribution of the gelatin, which is crucial for uniform capsule wall thickness and dome strength. The coated pins then pass through controlled drying stages to achieve the target moisture content. 4.Stripping and Trimming: Once dried, the gelatin films are stripped off the pins and trimmed to the appropriate length, forming the capsule's body and cap. 5.Joining and Printing: The trimmed capsule halves are joined, and if required, printed with identifying information such as product names,Sahasra Yogam's Manufacturing Capabilities Sahasra Yogam employs advanced techniques to enhance the quality and efficacy of their capsules: Granulation, Slugging, and Compacting: These processes are utilized to increase the bulk density of formulations, ensuring accurate dosing in each capsule. Encapsulation Machinery: The facility is equipped with semi-automatic encapsulation machines capable of producing up to 200,000 capsules per day, accommodating sizes 0, 00, and 1. Blister Packing: An integrated two-track automatic blister packing unit ensures timely delivery of finished products, with a packing capacity of 800,000 capsules per day.
Batch Printing: An in-house batch printing unit completes the full-fledged formulation manufacturing unit, providing end-to-end solutions. Advantages of Hard Gelatin and Vegetarian Capsules Both hard gelatin and vegetarian capsules offer several benefits: Ease of Swallowing: Their smooth and slippery surface makes them easy to swallow, ideal for individuals who have difficulty swallowing tablets. Versatility: They can be filled with a wide range of materials, including powders, liquids, semi-solids, and even small objects like beads or pellets. Protection: Capsules provide a protective barrier around the active ingredients, helping to prevent degradation due to moisture, light, or air. Customization: Capsules can be customized in terms of size, shape, and Bioavailability: Designed to dissolve quickly in the stomach, capsules release active ingredients for rapid absorption into the bloodstream, which can increase their bioavailability compared to other forms of medication. Conclusion Sahasra Yogam'sdedication to quality and innovation in the manufacturing of hard gelatin and vegetarian capsules positions them as a trusted partner in the pharmaceutical and nutraceutical industries. Their state-of-the-art facilities and adherence to stringent manufacturing processes ensure that they meet the diverse needs of their clientele, delivering products that are both effective and safe.