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Figure 1 The products of two genes are required to reconstitute basic telomerase activity; the RNA component, hTR, which includes the template for synthesis of telomere DNA, and the protein catalytic component, hTERT, which has reverse transcriptase activity.

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Figure 1 The products of two genes are required to reconstitute basic telomerase activity; the RNA component, hTR, which includes the template for synthesis of telomere DNA, and the protein catalytic component, hTERT, which has reverse transcriptase activity

Keith WN et al. (2004) Drug Insight: cancer cell immortality-telomerase as a target for novel cancer gene therapies.Nat Clin Pract Oncol 1: 88–96 doi:10.1038/ncponc0044