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Non-Mendelian Inheritance

Non-Mendelian Inheritance

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Non-Mendelian Inheritance

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  1. Non-Mendelian Inheritance Extranuclear genes Mitochondria Chloroplasts Epigenetic phenomenon Impacts expression of genes or development 1

  2. Mitochondrial Inheritance Maternal inheritance in most organisms - cytoplasmic donor Mitochondrial Eve - common African ancestor > 150,000 years ago 2

  3. Mitochondrial Mutations in Humans Many diseases associated with defects in mitochondria Some also caused by nuclear genes 3

  4. Maternal Inheritance in Neurospora Poky mutants - defective cytochromes in mitochondria Phenotype of mother appears in all offspring 4

  5. Transmission of Chloroplasts Plants often uniparental inheritance Angiosperms (flowering) Most maternal inheritance Some from both (biparental) Few mostly paternal (evening primrose) Conifers (gymnosperms) Mostly paternal inheritance 5

  6. Transmission of Chloroplasts Shoot color in four o’clock plants - variegation 6

  7. Transmission of Chloroplasts Shoot color in four o’clock plants - maternal inheritance 7

  8. Transmission of Chloroplasts Variegation due to heteroplasmy 8

  9. Petite Mutations in Yeast Nuclear Inheritance Uniparental inheritance of mitochondria 9

  10. Infectious Heredity Microorganisms coexist symbiotically with host Killer phenomenon in yeast toxin L helps M replicate 10

  11. Maternal Effect Mother’s genotype determines phenotype of progeny Shell coiling in snails 11

  12. Maternal Effect Hermaphrodites D- mother dextral offspring dd mother sinistral offspring 12