Absorption, Distribution  Biotransformation II. Biotransformation Microsomal enzymes Phase I reactions hydrolysis,oxidat Preloader

Absorption, Distribution Biotransformation II. Biotransformation Microsomal enzymes Phase I reactions hydrolysis,oxidat - PowerPoint PPT Presentation


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BiotransformationEnzyme mediatedPrerequisite to excretion (incr. water solubility)Rarely complete to CO2 H2OMetabolites can be more toxic. Microsomal EnzymesSmooth endoplasmic reticulum (espec. liver)

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