1 / 7

FET might be susceptible to an imperfect environment

Mohak IVF- test tube baby center is one of the Best infertility hospital in indore provides infertility treatment with high international standards and assisted reproductive technologies like IUI, IVF/ ICSI treatment, IMSI etc. Mohak IVF provides high success ratio IVF treatment at affordable ivf cost in indore. Highly experienced and fully professionals ivf specialist/doctor in indore give their full efforts to make your parenthood dreams comes true.https://www.mohakivf.com

mohakiv
Download Presentation

FET might be susceptible to an imperfect environment

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. FET might be susceptible to an imperfect environment MohakLaparoscopy and Infertility Center

  2. FET might be susceptible to an imperfect environment

  3. “Can FET and fresh ET outcome in IVF cycles be affected by the open environment air pollution?” INTRODUCTION: IVF outcomes and human infertility can be a result of air pollution around us. It’s indicated in Choe et al [1] study that lower pregnancy rates in IVF cycles can be associated with ambient air pollution while controlled ovarian stimulation as well as the post-transfer period. Choe et al1 study indicated lower pregnancy rates in IVF cycles may be linked to ambient air pollution during controlled ovarian stimulation and the post-transfer period. Do the outcomes of frozen-thawed embryo transfer (FET) and fresh transfer are differentially affected by open-air pollution?

  4. SUMMARY:Between January 2013 and December 2016, Wang et al [2] studied the adverse effects of air pollution in 11148 patients contributing to 16290 transfer cycles for IVF treatment cycles. The average age of the cohort was recorded to be 31.5 years. In order to estimate the daily ambient exposures to six main pollutants ( CO, O 3 , SO 2 , NO 2 , PM 2.5 , PM 10 ) inverse distance weighing interpolation was used at an IVF clinical site, bestow to the data recorded at the fixed air quality monitoring stations inside the city. The exposure for every cycle was shown as the daily mean concentration of contaminants (pollutants) from oocyte retrieval to embryo transfer/cryopreservation. Analysis of exposures was performed on every quarter basis. A general equating estimate was used to study the relationship between pollutants and IVF results. The rate of clinical pregnancy and the rate of live birth of the course were recorded to be 55.1% and 47.1% respectively. 4013 patients among the included cycles, got 5299 FET cycles, bringing about 42.7% live birth per ET, while 9553 patients got 10991 new transfer cycles, bringing about 49.2% to live birth per ET. Raised SO 2 and O 3 levels were essentially related with lower rates of live birth in FET cycles, while none of the pollutants was significantly linked with bringing down of IVF results in new transfer cycles. The FET cycles in the most elevated quartile of SO 2 and O 3 exposure had essentially lower rates of live birth (balanced OR) in correlation with those in the least quartile. Models including all transfer cycles and collaboration terms (FET exposures) recommended that FET altogether improved the impacts of SO 2 and O 3 exposures on IVF results (P < 0.001). Representing every six contaminations, women in the top quartile of SO 2 still had the least rates of live birth (OR 0.61, 95%CI 0.47–0.80).

  5. CONCLUSION: According to this study, embryos may be more vulnerable to a suboptimal environment which are undergoing FET in comparison to those which are undergoing fresh transfer. Elevated SO 2 and O 3 levels at the location of IVF were found to be significantly linked with lower rates of live birth following FET whereas it did not show any adverse effect on the contemporary new transfer results. In the locations and seasons which are heavily polluted, due to dynamic changes of the ambient air pollutant (specifically gaseous), fluctuation in FET outcomes can be seen. REFERENCES: 1. Xin Li Wang, JialiCai, Lanlan Liu, Xiaoming Jiang, Ping Li, AiguoSha, JianzhiRen; Association between outdoor air pollution during in vitro culture and the outcomes of frozen-thawed embryo transfer, Human Reproduction, Volume 34, Issue 3, 1 March 2019, Pages 441–451, https://doi.org/10.1093/humrep/dey386  2. Choe SA, Jun YB, Lee WS, Yoon TK, Kim SY. Association between ambient air pollution and pregnancy rate in women who underwent IVF. Hum Reprod. 2018 Jun 1;33(6):1071-1078. doi: 10.1093/humrep/dey076. PubMed PMID: 29659826

  6. Mohaklaparoscopy and infertility center, part of a multispecialty advanced care facility, is the best infertility hospital in Indore. Mohak IVF is the best fertility center in Indore, India with advanced technology, interactive & caring hospitality and great success rate. The affordable IVF treatment cost makes it preferential for the couples in need of infertility treatment, Test-tube Baby treatment, and IVF treatment. The IVF specialist, doctors and the professional staff of center offers IVF, andrology, embryology, assisted reproductive technology, ICSI treatment and also offers IVF financing at our fertility center. To book an appointment with the Doctors/ best IVF specialist at the best IVF center in MP, Indore, Call- 78980-47572 / 80852-77666 MohakIVF- test tube baby center is one of the Best infertility hospital in indore provides infertility treatment with high international standards and assisted reproductive technologies like IUI, IVF/ICSI treatment, IMSI etc. Mohak IVF provides high success ratio IVF treatment at affordable ivf cost in indore. Highly experienced and fully professionals ivf specialist/doctor in indore give their full efforts to make your parenthood dreams comes true.

More Related