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Fructose & Diabetes

Fructose & Diabetes. Go to www.sweetenerstudies.com/AADE to download these slides for your presentations. Studies on Fructose And Diabetes. Effect of fructose on glycemic control in diabetes.  Cozma AI et al. Diabetes Care . 2012;35:1611-1620.

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Fructose & Diabetes

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  1. Fructose & Diabetes Go to www.sweetenerstudies.com/AADEto download these slides for your presentations.

  2. Studies on Fructose And Diabetes • Effect of fructose on glycemic control in diabetes.  • Cozma AI et al. Diabetes Care. 2012;35:1611-1620. • “In conclusion, aggregate analyses of short-term controlled feeding trials showed that isocaloric fructose replacement of other carbohydrates resulted in clinically significant improvements in glycemic control, equivalent to a ~0.53% reducing in HbA1c, without significantly affecting insulin in diabetic individuals.” (pg 1618)

  3. Studies on Fructose And Diabetes • Effect of fructose on body weight in controlled feeding trials. • Sievenpiper JL et al. Annals of Internal Medicine. 2012;156:291-304. • “Fructose does not seem to cause weight gain when it is substituted for other carbohydrates in diets providing similar calories.” (pg 291) • “In conclusion, aggregate data analysis of controlled feeding trials do not support a body weight-increasing effect of fructose in isocaloric exchange for other sources of carbohydrate in the diet.” (pg 301)

  4. Studies on Fructose And Diabetes • Evidence-based review on the effect of normal dietary consumption of fructose on development of hyperlipidemia and obesity in healthy, normal weight Individuals.  • Dolan LC, Potter SM, Burdock GA. Critical Reviews in Food Science and Nutrition. 2010;50:53-84. • “The authors concluded that small amounts of fructose improve the glycemic response to an oral glucose load without altering the insulin or TG response.” (pg 66)

  5. Studies on Fructose And Diabetes • Effect of fructose on blood pressure: a systematic review and meta-analysis of controlled feeding trials.  • Ha V et al. Journal of the American Heart Association. 2012:59:1-9. • “The hypercaloric fructose feeding trials found no significant overall mean arterial blood pressure effect of fructose in comparison with other carbohydrates.” (pg 1)

  6. Studies on Fructose And Diabetes • The effects of fructose intake on serum uric acid vary among controlled dietary trials.  • Wang DD et al. The Journal of Nutrition. 2012;142:916-923. • The “These analyses do not support a uric-acid increasing effect of isocaloric fructose intake in nondiabetic and diabetic participants.” (pg 916) • “In conclusion, our work suggests that contrary to concerns, isocaloric fructose exchange for other sources of carbohydrate does not raise uric acid concentrations and this lack of effect holds across different experimental conditions.” (pg 921)

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