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Structure of DNA & Point Mutations

Structure of DNA & Point Mutations. Text ref 6.1 and 6.2. The Chemical Composition of DNA. Three main components: Pentose sugar (5 carbon ring) Phosphate group with negative charge Nitrogenous base. Three components together = nucleotide

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Structure of DNA & Point Mutations

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  1. Structure of DNA & Point Mutations Text ref 6.1 and 6.2

  2. The Chemical Composition of DNA • Three main components: • Pentose sugar (5 carbon ring) • Phosphate group with negative charge • Nitrogenous base

  3. Three components together = nucleotide • DNA is made of MANY nucleotides in repeating units!

  4. 4 types of nitrogenous bases: T C A G

  5. DNA structure: • Amount of A = T • Amount of G = C • DNA has a phosphate-sugar “backbone”, and bases that “pair up” in the middle of the molecule. • A always pairs with T • G always pairs with C

  6. DNA is always double stranded and in a helix.

  7. Strands of DNA are always complementary • This means they “match up” • Ribosomes read DNA in groups of three nucleotides = instructions to build proteins!

  8. Point Mutations • Replicating cells do not copy genetic info in DNA accurately. • Three major types of point mutations: • Base-pair substitutions • Insertions • Deletions

  9. Base-Pair Substitutions: • One nitrogenous base is accidently replaced with another base.

  10. Insertions: • One or more nitrogenous base(s) is inserted during the copying process.

  11. Deletions: • One or more nitrogenous base(s) is deleted during the copying process.

  12. Homework • Page 233 #2, 4 • Page 239 #2, 3

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