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NIH PCKD/Emory University

NIH PCKD/Emory University. MRI Imaging Report 1/31/2000. Overview. 2 Patients Scanned with NIH Protocol Both: Comparison with “Old Protocol” Visual comparison No SNR measurements performed No Breathhold Flow Quantification (Yet) Philips scanner should be capable

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NIH PCKD/Emory University

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  1. NIH PCKD/Emory University MRI Imaging Report 1/31/2000

  2. Overview • 2 Patients Scanned with NIH Protocol • Both: Comparison with “Old Protocol” • Visual comparison • No SNR measurements performed • No Breathhold Flow Quantification (Yet) • Philips scanner should be capable • Little experience; Validation experiments?

  3. T2-Weighted Multi-Slice (#1) Old Protocol (3 mm) Multiple Breathholds NIH Protocol (5 mm) Single Breathhold

  4. T2-Weighted Multi-Slice (#2) Old Protocol (3 mm) Multiple Breathholds NIH Protocol (5 mm) Single Breathhold

  5. T2-Weighted Imaging: Remarks • 3 mm slice thickness resolves cysts better • Fat Suppression useful, works well • Multiple-breathhold: registration needed • Kidney “rigid object”: overlap + affine Xform • Avoid misregistration between interlaced stacks • Role in image analysis?

  6. T1-Weighted 3-D (PRE-#1) Old Protocol (2.5/5 mm) =40 Single Breathhold NIH Protocol (2.5/5 mm) =12 Single Breathhold

  7. T1-Weighted 3-D (PRE-#2) Old Protocol (2.5/5 mm) =40 Single Breathhold NIH Protocol (2.5/5 mm) =12 Single Breathhold

  8. T1-Weighted 3-D (POST-#1) Old Protocol (2.5/5 mm) =40 90 s post-Gado NIH Protocol (2.5/5 mm) =12 120 s post-Gado

  9. T1-Weighted 3-D (POST-#2) Old Protocol (2.5/5 mm) =40 60 s post-Gado NIH Protocol (2.5/5 mm) =12 120 s post-Gado

  10. T1-Weighted 3-D heart liver Ghost artifact due to heart motion (?) Apply pre-saturation slab anterior to volume to reduce intensity?

  11. T1-Weighted Imaging: Remarks • NIH protocol (=12) better overall SNR • Pre- & post-contrast: more complex image • Segmentation easier? (CNR measurements) • Coil placement important! Difficult? • Pre-saturation slabs? Added acq. time? • Older patients: • Many breathholds taxing to patient • Only 90 or 120 s post contrast?

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