Definition. A skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fracture. NIH Consensus Statement 2000. Diagnostic Criteria. Bone mineral density (BMD) 2.5 standard deviations below the mean bone mineral density of healthy, young, white women (T-score of -2.5) or Fracture in the absence of significant trauma in a postmenopausal woman World Health Organization working group 1992.
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