1 / 9

Case 9

Case 9. Clinical data. 50-year-old male with prostatic symptomatology PSA serum level-normal Homogenous, enlarged soft prostate No focal changes were revealed ultrasonographically Needle biospy: 12 reprezentative samples 11-21 mm. ???. Striped Basilisc Basiliscus vittatus.

melvyn
Download Presentation

Case 9

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Case 9

  2. Clinical data • 50-year-old male with prostatic symptomatology • PSA serum level-normal • Homogenous, enlarged soft prostate • No focal changes were revealed ultrasonographically • Needle biospy: 12 reprezentative samples 11-21 mm

  3. ???

  4. Striped Basilisc Basiliscus vittatus

  5. Immunohistochemistry • EMA, AE1-AE3, vimentin-slightly positive • Negative PSA, PAPH, CD 99

  6. fusion SYT-SSX-positive FISH (event. RT-PCR)

  7. Primary synovial sarcoma of the prostate

  8. Synovial sarcoma • Synovial sarcoma is characterised by specific translocation t(X;18), resulting fusion of gene SYT (18q11) and related genes SSX1 (Xp11.23), resp. SSX2 (Xp11.21). • SYT-SSX1 for bifasic SS • SYT-SSX2 for monophasis SS

  9. Diferential diagnostics • Leiomyosarcoma of the prostate/ leiomyoma • Postoperative spindle cell nodulus • Sarcomatoid TCC • Phylloid tumor of the prostate

More Related