Thrombocytopenia in the NICU. EMAD LAWENDY MD PGY2 October 2009. Aim of this PowerPoint. Discuss the incidence of neonatal thrombocytopenia. Describe the risks of a low platelet count in neonates .
EMAD LAWENDY MD
Traditionally defined as platelet count < 150.000 /mcL ( mild < 100.000 and moderate 50.000-99.000/mcL)
If the mother has autoimmune thrombocytopenia -- the most likely diagnosis in an otherwise well appearing neonate is autoimmune thrombocytopenia mediated by the placental passage of maternal autoantibodies .
Thrombocytopenia can be the first presenting sign of a serious condition many clinicians order blood cultures and consider administering antibiotics for well appearing neonates in whom the cause of the thrombocytopenia is not yet clearly defined.
Blood should be collected from the mother and the father and submitted for confirmatory testing.
The neonates serum can be screened for platelet antibodies if blood from the parents is not available ( may give false negative result).
If the patient is stable + no evidence of ICH PLT transfusion if the PLT count is < 30,000.