forensic toxicology n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Forensic Toxicology PowerPoint Presentation
Download Presentation
Forensic Toxicology

Loading in 2 Seconds...

play fullscreen
1 / 17

Forensic Toxicology - PowerPoint PPT Presentation


  • 528 Views
  • Uploaded on

Forensic Toxicology. Objectives. Identify the 5 types of controlled substances Relate signs and symptoms of overdose with specific class of drugs or toxins Describe the role of various types of toxins in causing death Discuss agents that may be used in bioterrorism

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Forensic Toxicology' - matt


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
objectives
Objectives
  • Identify the 5 types of controlled substances
  • Relate signs and symptoms of overdose with specific class of drugs or toxins
  • Describe the role of various types of toxins in causing death
  • Discuss agents that may be used in bioterrorism
  • Define and describe the goals and practice of toxicology
vocabulary
Vocabulary
  • Controlled substance
  • Drug
  • Metabolism
  • Narcotic
  • Poison
  • Toxicity
  • Toxin
toxicology
Toxicology
  • Toxicology is the study of poisons and the identification of drugs and other substances a person may have used for various purposes
  • Examines the harmful affects of poisons and drugs on the body
forensic toxicologist
Forensic Toxicologist
  • Primary duty
    • Detect and identify drugs and poisons in body fluids, tissues, and organs
exposure
Exposure
  • Drugs/toxins exposed by
    • Ingesting so they enter the gastrointestinal system
    • Inhaling them into lungs
    • Injecting them into the bloodstream
    • Absorbing them through skin
toxicity
Toxicity
  • Toxicity
    • The degree to which a substance is poisonous or can cause injury
  • Factors
    • Dose
    • Duration
    • Nature of exposure
    • Other
classification of toxins
Classification of Toxins
  • Intentionally
    • Treat illness or pain relief
  • Accidentally
    • Ingested or exposed (harmful combo)
  • Deliberately
    • Suicide or purposing harming others
brief history
Brief History
  • Dates back to ancient Greece
  • 17th century
    • Poisoning became profession
    • Arsenic and cyanide “inheritance powder”
  • 19th century-chemical analysis began
  • Mathieu Orfila & Robert Christison
metabolism of drugs
Metabolism of Drugs
  • All chemicals that enter the body are broken down by chemicals in the body
  • Metabolism (transformation of chemical)
    • Absorption
      • Through blood stream
    • Distribution
      • Carried to all parts of the body
    • Elimination
      • Oxidation takes place in the liver
murder by poison
Murder by Poison
  • Less than ½ of 1% of all homicide result from poisoning
  • Acute poisoning
    • High does over short period of time
  • Chronic poisoning
    • Lower dose over long period of time
drugs crime
Drugs & Crime
  • Controlled substance
    • Legal drugs whose sales, possession, and use are restricted because of the effect of the drugs and the potential for abuse
      • Narcotics
      • Depressants
      • Stimulants
production of poison
Production of Poison
  • Living organism
    • Alcohol
      • Ethyl alcohol
    • Bacteria
      • Botulism
      • tetanus
metal poison
Metal Poison
  • Heavy metals
    • Absorbed by ingestion, inhalation, or absorb through skin
      • Arsenic
      • Lead
      • Mercury
  • Gases
      • Hydrogen cyanide
      • Carbon monoxide
      • Potassium chloride
      • Sodium pentathal
bioterrorism
Bioterrorism
  • Ricin (waste from castor oil and castor bean)
    • Difficulty breathing, nausea, fever, cough, excess fluid in lungs, dehydration
    • Lethal
  • Anthrax (bacillus anthracis)
    • 25-60% fatal if ingested
    • Flu-like symptoms
collection preservation of blood
Collection & Preservation of Blood
  • Must be collected under medically accepted conditions
  • Sealed in airtight container & addition of anticoagulant & preservative
  • Stored in refrigerator & delivered to lab
research case study
Research Case Study
  • Research one of the following cases related to toxicology
    • Provide summary of case
    • Drugs/toxins involved in case (stimulants, depressant, etc)
    • Outcome (accidental, deliberate, intentional)
    • Resources cited
  • Mary Ansell (1899)
  • Eva Rablen (1929)
  • Death of Georgi Markov (1978) and Attack on Vladimir Kostove (1978)
  • Tylenol Tampering (1982)