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Sickle Cell Disease (SCD) is a genetic disorder causing lifelong blood syndromes due to hemoglobin defects. Affecting 1 in 500 African American newborns, it leads to abnormally shaped red blood cells, reducing cell flexibility and resulting in various health complications. There are four main types, including Sickle Cell Anemia (SS) and Sickle-Hemoglobin C Disease (SC). The disease is inherited through mutated genes, particularly in regions where malaria is prevalent. Symptoms include painful episodes, anemia, dehydration, and skin disorders like jaundice.
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Sickle Cell Disease: • Sickle cell is a genetically transmitted disorder. It causes life-long blood syndromes because of defects in hemoglobin. It is a widespread disease and as per the latest statistics, sickle cell disease is found in one out of every 500 new born babies amongst African-Americans. The disorder is marked by abnormal sickle shaped red blood cells. This in turn adversely affects flexibility in the cells leading to several health complications.
Types and causes • There are chiefly four kinds of sickling of cells. They are Sickle Cell Anemia (SS), Sickle-Hemoglobin C Disease (SC). Sickle cell disease is caused chiefly due to a form of mutation in the genes that had apparently originated in places where malarial was a common disease. It is purely genetically transferred from parents to the children.
Symnotyms • Pain • Anemia- dehydration/ fever • Skin disorder- it includes jaundice, yellowing of mouth, eyes and other parts of the skin.
