The Acute Abdomen. Major causes of the 'acute abdomen'. Acute cholecystitis Acute appendicitis or Meckel's diverticulitis Acute pancreatitis Peptic ulcer disease Pelvic inflammatory disease Intestinal obstruction , including paralytic ileus (adynamic obstruction)
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-Gallbladder disease and excess alcohol consumption account for most cases and typically cause periductal necrosis.
Biliary disease and alcohol abuse together account for 70%-80% of cases,