PPARGC1β is a Genetic Determinant of the Cardiovascular Risk Factor, Thromboxane A 2 – an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Sub-study.
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PPARGC1β is a Genetic Determinant of the Cardiovascular Risk Factor, Thromboxane A2 –
an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Sub-study
Nina McCarthy1, Ciara Vangjeli1, Praveen Surendran1,4, Achim Treumann1, Cathy Rooney1, Emily Ho1, Peter Sever2, Simon Thom2, Alun Hughes2, Patricia Munroe3, Philip Howard3, Toby Johnson3, Mark Caulfield3, Denis Shields4, Eoin O’Brien4, Desmond Fitzgerald4, Alice Stanton1.
1Royal College of Surgeons in Ireland, Dublin 2, Ireland
2Imperial College London, London W21LA, UK
3Barts and The London, Queen Mary's School of Medicine and Dentistry,
London EC1M 6BQ, UK
4 University College Dublin, Dublin 4, Ireland
linear regression analysis, adjusting for the covariates;
Population Characteristics Risk Factor, Thromboxane A
Results: Manhattan Plots Risk Factor, Thromboxane A
PPARGC1 Risk Factor, Thromboxane Aβ Peak
TNF-α, IL-6, IL-1β
MCP-1, VCAM, ICAM