1 / 28

The COSMIN study COnsensus-based Standards for the selection of health status Measurement INstruments

The COSMIN study COnsensus-based Standards for the selection of health status Measurement INstruments. Wieneke Mokkink, Caroline Terwee, Paul Stratford, Jordi Alonso, Donald Patrick, Dirk Knol, Lex Bouter, Riekie de Vet. Outline presentation. Background Methodological guidelines

lynsey
Download Presentation

The COSMIN study COnsensus-based Standards for the selection of health status Measurement INstruments

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. The COSMIN studyCOnsensus-based Standards for the selection of health status Measurement INstruments Wieneke Mokkink, Caroline Terwee, Paul Stratford, Jordi Alonso, Donald Patrick, Dirk Knol, Lex Bouter, Riekie de Vet

  2. Outline presentation • Background • Methodological guidelines • COSMIN Delphi Study • Purpose • Methods • Preliminary results

  3. Why methodological guidelines? Importance of high-quality studies • Detection of potential bias that may influence the results • Better and more realistic estimates of results • Greater acceptance of results in health care community Moher et al. Controlled Clinical Trials 1995;16:62-73

  4. Accepted guidelines • RCT: Delphi List (Verhagen et al.) • Diagnostic research: QUADAS

  5. Why a new guideline? • Several checklists for measurement properties exist (SAC MOS/Lohr, Bombardier & Tugwell, Andresen, Terwee) • No consensus on terminilogy and defintions • None is generally accepted and widely used • Most chance of getting enough support is by developing a checklist in an international consensus study, i.e. a Delphi Study

  6. Aim of the COSMIN study 1. Which measurements properties should be included in the assessment of evaluative HR-PROs, and how should they be defined? 2. How should these measurement properties be assessed in terms of study design and statistical analysis? (i.e. standards) Available as a checklist

  7. Methods (1) • International Delphi study • Steering committee • Background panel members: • clinical medicine • biostatistics • psychology (psychometrics) • epidemiology (clinimetrics)

  8. Methods (2) Design delphi rounds: • Four written rounds • which measurement properties (term and definitions) • how selected properties should be assessed (standards) • achieve consensus on complete checklist • 5 point scale + arguments and comments • strongly disagree/disagree/no opinion/agree/strongly agree • Consensus: ≥67% (strongly) agreed

  9. Focus of COSMIN HR-PRO instruments used in an evaluative application • PRO: endpoint derived from patient report • HR: not adherence or satisfaction with care

  10. Invited: N=91 Agreed to participate: N=57 Flow chart

  11. Invited: N=91 Agreed to participate: N=57 Drop out: N=3 Round 1: N=57 Responses: N=42 (74%) Drop out: N=2 Round 2: N=54 Responses: N=31 (58%) Drop out: N=1 Round 3: N=52 Responses: N=25 (48%) Round 4: N=51 Responses: N=27 (53%) Flow chart

  12. Products of COSMIN • Taxonomy (consensus on terms and definitions) • COSMIN checklist

  13. Reliability

  14. Content validity Construct validity Criterion validity structural validity* concurrent validity hypotheses testing, e.g. convergent validity, divergent validity, known group validity face validity predictive validity cross-cultural validity† * necessary for multi-item instruments, † necessary for cross-cultural comparison Validity

  15. Responsiveness

  16. Results (2) Structure COSMIN checklist 3 Sections: • Descriptive information about the HR-PRO instrument • Descriptive information about a study of a measurement property • Evaluation of methodological quality of studies of measurement properties, i.e. standards

  17. Section 1 Descriptive information of the HR-PRO instrument • Development process • Format • Translation process • Interpretability

  18. Example (1)

  19. Section 2 Descriptive information of the study • IRT study

  20. Example (2)

  21. Section 3 Evaluation of methodological quality of the studies • Term • Definition • Standard • design requirement • statistical analysis

  22. Standard for internal consistency

  23. Future • Selecting an HR-PRO instrument • Content • Practical issues • Measurement properties • Standards • Criteria of adequacy for good measurement properties • Inter-rater reliability study of COSMIN checklist

  24. Neil Aaronson Linda Abetz Elena Andresen Dorcas Beaton Martijn Berger Giorgio Bertolotti Monika Bullinger David Cella Joost Dekker Dominique Dubois Anne Evers Diane Fairclough David Feeny Raymond Fitzpatrick Andrew Garratt Francis Guillemin Dennis Hart Graeme Hawthorne Ron Hays Elizabeth Juniper Robert Kane Donna Lamping Marissa Lassere Matthew Liang Kathleen Lohr Patrick Marquis Chris McCarthy Elaine McColl Ian McDowell Don Mellenbergh Mauro Niero Geoffrey Norman Manoj Pandey Luis Rajmil Bryce Reeve Dennis Revicki Margaret Rothman Mirjam Sprangers David Streiner Gerold Stucki Giulio Vidotto Sharon Wood-Dauphinee Albert Wu Many thanks to …

More Related